1. Others
  2. Others
  3. Ibrutinib-MPEA

Ibrutinib-MPEA 

Cat. No.: HY-43521 Purity: 98.23%
Handling Instructions

Ibrutinib-MPEA (Compound 20) is ibrutinib derivative. Ibrutinib is a covalent and irreversible inhibitor of Bruton's tyrosine kinase (BTK) that has been used to treat haematological malignancies.

For research use only. We do not sell to patients.

Ibrutinib-MPEA Chemical Structure

Ibrutinib-MPEA Chemical Structure

CAS No. : 1710768-30-1

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 787 In-stock
Estimated Time of Arrival: December 31
5 mg USD 615 In-stock
Estimated Time of Arrival: December 31
10 mg USD 1077 In-stock
Estimated Time of Arrival: December 31
25 mg USD 2154 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Ibrutinib-MPEA (Compound 20) is ibrutinib derivative. Ibrutinib is a covalent and irreversible inhibitor of Bruton's tyrosine kinase (BTK) that has been used to treat haematological malignancies[1].

Molecular Weight

581.71

Formula

C₃₂H₃₉N₉O₂

CAS No.

1710768-30-1

SMILES

NCCN1CCN(C/C=C/C(N2C[[email protected]](N3N=C(C4=CC=C(OC5=CC=CC=C5)C=C4)C6=C(N)N=CN=C63)CCC2)=O)CC1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 33.33 mg/mL (57.30 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7191 mL 8.5953 mL 17.1907 mL
5 mM 0.3438 mL 1.7191 mL 3.4381 mL
10 mM 0.1719 mL 0.8595 mL 1.7191 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 3.33 mg/mL (5.72 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 3.33 mg/mL (5.72 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 98.23%

  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Ibrutinib-MPEAOthersInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Ibrutinib-MPEA
Cat. No.:
HY-43521
Quantity:
MCE Japan Authorized Agent: