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Cat. No.: HY-158303

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Chk2-IN-2

Chk2-IN-2 (compound 2) is a selective inhibitor of CHK2 with potential anticancer activity.

For research use only. We do not sell to patients.

CAS No.: 2984543-29-3
Formula: C₂₀H₁₉F₅N₈O
Molecular Weight:482.41

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Chk2-IN-2 Chemical Structure

CAS No.: 2984543-29-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Chk2-IN-2 (compound 2) is a selective inhibitor of CHK2 with potential anticancer activity^[1].

IC₅₀ & Target^[1]

Chk2

All Checkpoint Kinase (Chk) Isoforms :

Chemical Information

CAS No. 2984543-29-3
Molecular Weight 482.41
Formula C₂₀H₁₉F₅N₈O
SMILES

FC1=C(C2=NC(C(N[C@H]3C[C@@H](CNC3)F)=O)=C(N=C2)N)C=C(C4=CN(N=C4)CC(F)(F)F)N=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Preparation of 3-aminopyrazine-2-carboxamide derivatives and use thereof for inhibiting checkpoint kinase 2. World Intellectual Property Organization, WO2023177233 A1 2023-09-21.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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Chk2-IN-2

All Checkpoint Kinase (Chk) Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Chk2-IN-2 Related Classifications

HY-158303 Related Classifications