1. Signaling Pathways
  2. Cell Cycle/DNA Damage
  3. Checkpoint Kinase (Chk)
  4. Chk2 Inhibitors

Chk2 Inhibitors

Chk1

Chk2

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform Chk2 together.

Please try each isoform separately.

Chk2 Specific Inhibitors & Activators
Product Name Chk2 Chk1 Chk2 Selectivity Purity
BML-277
Chk2, IC50: 15 nM
  Selective Inhibitor 98.02%
CCT241533 hydrochloride
Chk2, IC50: 3 nM
Chk2, Ki: 1.16 nM
Chk1, IC50: 245 nM
Selective Inhibitor 99.98%
ANI-7
Chk2
  Selective Activator 99.25%
CCT241533
Chk2, IC50: 3 nM
Chk2, Ki: 1.16 nM
Chk1, IC50: 245 nM
Selective Inhibitor
VER-00158411
Chk2, IC50: 4.5 nM
Chk1, IC50: 4.4 nM
Selective Inhibitor
CCT241533 dihydrochloride
Chk2, IC50: 3 nM
Chk2, Ki: 1.16 nM
Chk1, IC50: 245 nM
Selective Inhibitor
Prexasertib
Chk2, IC50: 8 nM
Chk1, IC50: <1 nM
Chk1, Ki: 0.9 nM
Pan Inhibitor 98.22%
AZD-7762
Chk2, IC50: 5 nM
Chk1, IC50: 5 nM
Pan Inhibitor 99.95%
Rabusertib
Chk2, IC50: 12000 nM
Chk1, IC50: 7 nM
Pan Inhibitor 99.69%
Prexasertib dihydrochloride
Chk2, IC50: 8 nM
Chk1, IC50: <1 nM
Chk1, Ki: 0.9 nM
Pan Inhibitor 99.41%
SCH900776
Chk2, IC50: 1500 nM
Chk1, IC50: 3 nM
Pan Inhibitor 99.97%
Prexasertib dimesylate
Chk2, IC50: 8 nM
Chk1, IC50: <1 nM
Chk1, Ki: 0.9 nM
Pan Inhibitor
CCT245737
Chk2, IC50: 2440 nM
Chk1, IC50: 1.3 nM
Pan Inhibitor 99.24%
CHIR-124
Chk2, IC50: 697.4 nM
Chk1, IC50: 0.3 nM
Pan Inhibitor 98.07%
PF 477736
Chk2, Ki: 47 nM
Chk1, Ki: 0.49 nM
Pan Inhibitor 98.07%
Prexasertib Mesylate Hydrate
Chk2, IC50: 8 nM
Chk1, IC50: <1 nM
Chk1, Ki: 0.9 nM
Pan Inhibitor
CHK-IN-1
Chk2
Chk1
Pan Inhibitor