405168-58-3

CHIR-124 Chemical Structure
405168-58-3

Chemical Structure

CHIR-124

  • CAS. Nr.: 405168-58-3
  • Formula:C23H22ClN5O
  • Molecular Weight:419.91

IUPAC Name: (S)-3-(1H-benzo[d]imidazol-2-yl)-6-chloro-4-(quinuclidin-3-ylamino)quinolin-2(1H)-one

InChIKey: MOVBBVMDHIRCTG-LJQANCHMSA-N

SMILES: ClC1=CC2=C(NC(C(C3=NC4=C(C=CC=C4)N3)=C2N[C@@H]5CN6CCC5CC6)=O)C=C1

Biological Activity: CHIR-124 is a potent and selective Chk1 inhibitor with IC50 of 0.3 nM, and also potently targets PDGFR and FLT3 with IC50s of 6.6 nM and 5.8 nM.

Art. -Nr. Produktname Reinheit Beschreibung Pricing
HY-13263
CHIR-124 99.05% CHIR-124 is a potent and selective Chk1 inhibitor with IC50 of 0.3 nM, and also potently targets PDGFR and FLT3 with IC50s of 6.6 nM and 5.8 nM.
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