1262849-73-9
Chemical Structure
CCT241533
- CAS No.: 1262849-73-9
- Formula:C23H27FN4O4
- Molecular Weight:442.48
IUPAC Name: 4-fluoro-2-(4-(((3S,4R)-4-(2-hydroxypropan-2-yl)pyrrolidin-3-yl)amino)-6,7-dimethoxyquinazolin-2-yl)phenol
InChIKey: HZASIAXCPXTISQ-NVXWUHKLSA-N
SMILES: COC1=C(OC)C=C(C(N[C@H]2[C@H](C(C)(C)O)CNC2)=NC(C3=C(O)C=CC(F)=C3)=N4)C4=C1
Biological Activity: CCT241533 is a potent and selective ATP competitive inhibitor of CHK2 with an IC50 of 3 nM and Ki of 1.16 nM[1].
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CCT241533 | CCT241533 is a potent and selective ATP competitive inhibitor of CHK2 with an IC50 of 3 nM and Ki of 1.16 nM. | |||||||||||||||||||||
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Keywords