1. Signaling Pathways
  2. Cell Cycle/DNA Damage
  3. Checkpoint Kinase (Chk)
  4. Chk1 Inhibitors

Chk1 Inhibitors

Chk1

Chk2

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform Chk1 together.

Please try each isoform separately.

Chk1 Specific Inhibitors
Product Name Chk1 Chk2 Chk1 Selectivity Purity
Rabusertib
Chk1, IC50: 7 nM
Chk2, IC50: 12000 nM
Selective Inhibitor 99.69%
SCH900776
Chk1, IC50: 3 nM
Chk2, IC50: 1500 nM
Selective Inhibitor 99.97%
SB-218078
Chk1, IC50: 15 nM
  Selective Inhibitor >98.0%
CCT245737
Chk1, IC50: 1.3 nM
Chk2, IC50: 2440 nM
Selective Inhibitor 99.24%
CHIR-124
Chk1, IC50: 0.3 nM
Chk2, IC50: 697.4 nM
Selective Inhibitor 98.07%
PF 477736
Chk1, Ki: 0.49 nM
Chk2, Ki: 47 nM
Selective Inhibitor 98.07%
CCT244747
Chk1, IC50: 7.7 nM
  Selective Inhibitor >99.0%
PD 407824
Chk1, IC50: 47 nM
  Selective Inhibitor >98.0%
GDC-0575 dihydrochloride
Chk1, IC50: 1.2 nM
  Selective Inhibitor 99.83%
CHK1-IN-2
Chk1, IC50: 6 nM
  Selective Inhibitor
CHK1-IN-3
Chk1, IC50: 0.4 nM
  Selective Inhibitor
VER-00158411
Chk1, IC50: 4.4 nM
Chk2, IC50: 4.5 nM
Selective Inhibitor
Prexasertib
Chk1, IC50: <1 nM
Chk1, Ki: 0.9 nM
Chk2, IC50: 8 nM
Pan Inhibitor 98.22%
AZD-7762
Chk1, IC50: 5 nM
Chk2, IC50: 5 nM
Pan Inhibitor 99.95%
Prexasertib dihydrochloride
Chk1, IC50: <1 nM
Chk1, Ki: 0.9 nM
Chk2, IC50: 8 nM
Pan Inhibitor 99.41%
Prexasertib dimesylate
Chk1, IC50: <1 nM
Chk1, Ki: 0.9 nM
Chk2, IC50: 8 nM
Pan Inhibitor
MRT00033659
Chk1, IC50: 0.23 μM
  Pan Inhibitor
CCT241533 hydrochloride
Chk1, IC50: 245 nM
Chk2, IC50: 3 nM
Chk2, Ki: 1.16 nM
Pan Inhibitor 99.98%
CCT241533
Chk1, IC50: 245 nM
Chk2, IC50: 3 nM
Chk2, Ki: 1.16 nM
Pan Inhibitor
Prexasertib Mesylate Hydrate
Chk1, IC50: <1 nM
Chk1, Ki: 0.9 nM
Chk2, IC50: 8 nM
Pan Inhibitor
CHK1-IN-4
Chk1
  Pan Inhibitor
CCT241533 dihydrochloride
Chk1, IC50: 245 nM
Chk2, IC50: 3 nM
Chk2, Ki: 1.16 nM
Pan Inhibitor
CHK-IN-1
Chk1
Chk2
Pan Inhibitor