1657014-42-0

GDC-0575 dihydrochloride Chemical Structure
1657014-42-0

Chemical Structure

GDC-0575 dihydrochloride

Synonym(s): ARRY-575 dihydrochloride; RG7741 dihydrochloride

  • CAS No.: 1657014-42-0
  • Formula:C16H22BrCl2N5O
  • Molecular Weight:451.19

IUPAC Name: (R)-N-(4-(3-aminopiperidin-1-yl)-5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)cyclopropanecarboxamide dihydrochloride

InChIKey: OYMHZTORKRPOBI-YQFADDPSSA-N

SMILES: O=C(C1CC1)NC2=CNC3=NC=C(Br)C(N4C[C@H](N)CCC4)=C32.[H]Cl.[H]Cl

Biological Activity: GDC-0575 dihydrochloride (ARRY-575 dihydrochloride) is an orally bioavailable CHK1 inhibitor, with an IC50 of 1.2 nM, and has antitumor activity.

Cat. No. Product Name Purity Description Pricing
HY-112167A
GDC-0575 dihydrochloride 98.36% GDC-0575 dihydrochloride (ARRY-575 dihydrochloride) is an orally bioavailable CHK1 inhibitor, with an IC50 of 1.2 nM, and has antitumor activity.
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