Go 7874
Go 7874 is a protein kinase C (PKC) inhibitor. Go 7874 mediated neuroprotection against LPS/IFNg-induced neuronal cell death in an immune-mediated neurotoxicity model, not through PKC activity. In contrast, the neuroprotective mechanism of Go 7874 involves inhibition of inducible nitric oxide synthase (iNOS) gene expression, followed by reduced nitric oxide (NO) production.
For research use only. We do not sell to patients.
- CAS No.: 153207-86-4
- Formula: C27H26N4O4
- Molecular Weight:470.52
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 153207-86-4
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Molecular Weight 470.52
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Formula C27H26N4O4
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SMILES
O=C1NC(C2=C1C3=C(N(C4=C3C=C(C=C4)OC)CC(CN(C)C)O)C5=C2C6=C(C=CC=C6)N5C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)