1. Immunology/Inflammation
  2. COX
  3. Isoxicam

Isoxicam 

Cat. No.: HY-B1130 Purity: 99.11%
Handling Instructions

Isoxicam is an orally active, long-acting, non-steroidal anti-inflammatory agent for the research of arthritis. Isoxicam is a nonselective inhibitor of COX-1 and COX-2.

For research use only. We do not sell to patients.

Isoxicam Chemical Structure

Isoxicam Chemical Structure

CAS No. : 34552-84-6

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Description

Isoxicam is an orally active, long-acting, non-steroidal anti-inflammatory agent for the research of arthritis[1]. Isoxicam is a nonselective inhibitor of COX-1 and COX-2[2].

IC50 & Target[2]

COX-1

 

COX-2

 

Molecular Weight

335.34

Formula

C₁₄H₁₃N₃O₅S

CAS No.

34552-84-6

SMILES

O=C(C1=C(O)C2=CC=CC=C2S(N1C)(=O)=O)NC3=NOC(C)=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 5 mg/mL (14.91 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9820 mL 14.9102 mL 29.8205 mL
5 mM 0.5964 mL 2.9820 mL 5.9641 mL
10 mM 0.2982 mL 1.4910 mL 2.9820 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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This equation is commonly abbreviated as: C1V1 = C2V2

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Keywords:

IsoxicamCOXCyclooxygenaseInhibitorinhibitorinhibit

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