CA IX-IN-5
CA IX-IN-5 (compound 9) is a human carbonic anhydrase IX (hCA IX) inhibitor with a Ki of 7.4 nM against hCA IX and 25.0 nM against hCA II.CA IX-IN-5 functionally inhibits hCA IX and hCA II isoenzymes, with selectivity for hCA IX over hCA II.CA IX-IN-5 can be used for the research of breast, colorectal, glioblastoma, lung, head and neck, and cervical cancers.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C20H23ClN6O5S
- 分子量:494.95
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
CA IX-IN-5 (compound 9) (0.05-50 μM; 10 min) potently inhibits human carbonic anhydrase IX (Ki = 7.4 nM) with 3.4-fold selectivity over human carbonic anhydrase II[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
分子量 494.95
-
分子式 C20H23ClN6O5S
-
SMILES
COC1=CC(NC2=NC(NCCC3=CC=C(C=C3)S(=O)(N)=O)=NC(Cl)=N2)=CC(OC)=C1OC
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)