DCAF1 binder 1
Based on 1 Customer Validation
DCAF1 binder 1 is a selective for the CRL4 DCAF1 E3 ligase complex. DCAF1 binder 1 is a ligands for E3 Ligase, involving in targeted protein degradation (TPD).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.77%
- CAS 番号: 3053860-67-3
- 分子式: C28H35ClN6O
- 分子量:507.07
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Cereblon |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 3053860-67-3
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性状 Solid
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分子量 507.07
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分子式 C28H35ClN6O
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Color White to off-white
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SMILES
NCCNC1=NC(C2(C3=CC=C(C=C3)Cl)CCCCC2)=NC4=C1C=CC(N5CCN(CC5)C(C)=O)=C4
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 50 mg/mL (98.61 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (274 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 1.9721 mL | 9.8606 mL | 19.7211 mL | 49.3029 mL |
| 5 mM | 0.3944 mL | 1.9721 mL | 3.9442 mL | 9.8606 mL | |
| 10 mM | 0.1972 mL | 0.9861 mL | 1.9721 mL | 4.9303 mL | |
| 15 mM | 0.1315 mL | 0.6574 mL | 1.3147 mL | 3.2869 mL | |
| 20 mM | 0.0986 mL | 0.4930 mL | 0.9861 mL | 2.4651 mL | |
| 25 mM | 0.0789 mL | 0.3944 mL | 0.7888 mL | 1.9721 mL | |
| 30 mM | 0.0657 mL | 0.3287 mL | 0.6574 mL | 1.6434 mL | |
| 40 mM | 0.0493 mL | 0.2465 mL | 0.4930 mL | 1.2326 mL | |
| 50 mM | 0.0394 mL | 0.1972 mL | 0.3944 mL | 0.9861 mL | |
| 60 mM | 0.0329 mL | 0.1643 mL | 0.3287 mL | 0.8217 mL | |
| 80 mM | 0.0247 mL | 0.1233 mL | 0.2465 mL | 0.6163 mL |
DCAF1 binder 1 関連分類
HY-149934 関連分類
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