Methyl palmitoleate
Based on 1 publication(s) in Google Scholar
Methyl palmitoleate ((Z)-Methyl hexadec-9-enoate), a fatty acid methyl ester, is an analogue of Palmitoleate with cytoprotective and growth-promoting properties.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.40%
- CAS 番号: 1120-25-8
- 分子式: C17H32O2
- 分子量:268.43
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保管条件:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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溶剤 & 溶解度
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MedChemExpress（MCE）の使用を引用している文献 Methyl palmitoleate
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生物活性
Methyl palmitoleate inhibits the formation and aggregation of wax crystals, and improves the low-temperature fluidity of biodiesel as a biodiesel additive[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1120-25-8
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性状 Liquid (Density: 0.875 g/cm3)
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分子量 268.43
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分子式 C17H32O2
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Color Colorless to light yellow
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SMILES
O=C(OC)CCCCCCC/C=C\CCCCCC
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別名
(Z)-Methyl hexadec-9-enoate; Methyl cis-9-Hexadecenoate; パルミトレイン酸メチル
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Gut Microbes
PUFAs add fuel to Crohn's disease-associated AIEC-induced enteritis by exacerbating intestinal epithelial lipid peroxidation. [Abstract]2023 Dec;15(2):2265578. PMID: 37800577
溶剤 & 溶解度
DMSO : 100 mg/mL (372.54 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (9.31 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: 2.5 mg/mL (9.31 mM); Suspended solution; Need ultrasonic
This protocol yields a suspended solution of 2.5 mg/mL. Suspended solution can be used for oral and intraperitoneal injection.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
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参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.7254 mL | 18.6268 mL | 37.2537 mL | 93.1342 mL |
| 5 mM | 0.7451 mL | 3.7254 mL | 7.4507 mL | 18.6268 mL | |
| 10 mM | 0.3725 mL | 1.8627 mL | 3.7254 mL | 9.3134 mL | |
| 15 mM | 0.2484 mL | 1.2418 mL | 2.4836 mL | 6.2089 mL | |
| 20 mM | 0.1863 mL | 0.9313 mL | 1.8627 mL | 4.6567 mL | |
| 25 mM | 0.1490 mL | 0.7451 mL | 1.4901 mL | 3.7254 mL | |
| 30 mM | 0.1242 mL | 0.6209 mL | 1.2418 mL | 3.1045 mL | |
| 40 mM | 0.0931 mL | 0.4657 mL | 0.9313 mL | 2.3284 mL | |
| 50 mM | 0.0745 mL | 0.3725 mL | 0.7451 mL | 1.8627 mL | |
| 60 mM | 0.0621 mL | 0.3104 mL | 0.6209 mL | 1.5522 mL | |
| 80 mM | 0.0466 mL | 0.2328 mL | 0.4657 mL | 1.1642 mL | |
| 100 mM | 0.0373 mL | 0.1863 mL | 0.3725 mL | 0.9313 mL |
Methyl palmitoleate 関連分類
HY-W011688 関連分類
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