PDE5-IN-9
Based on 1 Customer Validation
PDE5-IN-9 (Compound 59) is a PDE5 inhibitor (IC50: 11.2 μM). PDE5-IN-9 shows interaction with Gln 817, Tyr 612, and Ala 767 amino acid residues. PDE5-IN-9 can be used for research of cardiovascular disease.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.0%
- CAS 番号: 157862-84-5
- 分子式: C18H14N4S
- 分子量:318.40
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
生物活性
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PDE5 |
化学情報
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CAS 番号 157862-84-5
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性状 Solid
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分子量 318.40
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分子式 C18H14N4S
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Color White to off-white
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SMILES
C1(C2=CC=CN=C2)=NC(NCC3=CC=CS3)=C4C=CC=CC4=N1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
DMSO : 100 mg/mL (314.07 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1407 mL | 15.7035 mL | 31.4070 mL | 78.5176 mL |
| 5 mM | 0.6281 mL | 3.1407 mL | 6.2814 mL | 15.7035 mL | |
| 10 mM | 0.3141 mL | 1.5704 mL | 3.1407 mL | 7.8518 mL | |
| 15 mM | 0.2094 mL | 1.0469 mL | 2.0938 mL | 5.2345 mL | |
| 20 mM | 0.1570 mL | 0.7852 mL | 1.5704 mL | 3.9259 mL | |
| 25 mM | 0.1256 mL | 0.6281 mL | 1.2563 mL | 3.1407 mL | |
| 30 mM | 0.1047 mL | 0.5235 mL | 1.0469 mL | 2.6173 mL | |
| 40 mM | 0.0785 mL | 0.3926 mL | 0.7852 mL | 1.9629 mL | |
| 50 mM | 0.0628 mL | 0.3141 mL | 0.6281 mL | 1.5704 mL | |
| 60 mM | 0.0523 mL | 0.2617 mL | 0.5235 mL | 1.3086 mL | |
| 80 mM | 0.0393 mL | 0.1963 mL | 0.3926 mL | 0.9815 mL | |
| 100 mM | 0.0314 mL | 0.1570 mL | 0.3141 mL | 0.7852 mL |