Ro 10-5824
Based on 2 publication(s) in Google Scholar
Ro 10-5824 is a potent and selective D4R partial agonist with a Ki of 5.2 nM. Ro 10-5824 increases novel object exploration in C57 mice.
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- CAS 番号: 189744-46-5
- 分子式: C17H20N4
- 分子量:280.38
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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MedChemExpress（MCE）の使用を引用している文献 Ro 10-5824
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生物活性
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Dopamine D4 receptor |
化学情報
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CAS 番号 189744-46-5
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分子量 280.38
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分子式 C17H20N4
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SMILES
N=1C=C(C(=NC1C)N)CN2CC=C(C=3C=CC=CC3)CC2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
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Journal Impact Factor
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Most Recent
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Br J Pharmacol
Requirement of sigma-1 receptor (Sig-1R) for boosting the gamma oscillations in the medial prefrontal cortex (mPFC). [Abstract]2026 Aug;183(15):4178-4195. PMID: 42025290 -
Brain Behav Immun
Neural network disturbance in the medial prefrontal cortex might contribute to cognitive impairments induced by neuroinflammation. [Abstract]2020 Oct:89:133-144. PMID: 32505714
純度とドキュメンテーション
参考文献
[1]. Powell SB, et al. RO-10-5824 is a selective dopamine D4 receptor agonist that increases novel object exploration in C57 mice. Neuropharmacology. 2003 Mar;44(4):473-81. [Content Brief]
[2]. Cummings DF, et al. Transmembrane segment five serines of the D4 dopamine receptor uniquely influence the interactions of dopamine, norepinephrine, and Ro10-4548. J Pharmacol Exp Ther. 2010 Jun;333(3):682-95. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Ro 10-5824 関連分類
HY-101384 関連分類
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