S-Propargylcysteine
Based on 1 Customer Validation
S-Propargylcysteine (SPRC), a structural analog of S-allyl cysteine (SAC), is a slow H2S-releasing compound. S-Propargylcysteine reduces Ca2+ accumulation and inflammatory cytokines, inhibits STAT3, and elevates p53 and Bax. S-Propargylcysteine has anti-inflammatory activity and protects mice against acute pancreatitis. S-Propargylcysteine also has cardioprotective, neuroprotective acitivties.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 97.0%
- CAS 番号: 3262-64-4
- 分子式: C6H9NO2S
- 分子量:159.21
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
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生物活性
化学情報
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CAS 番号 3262-64-4
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性状 Solid
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分子量 159.21
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分子式 C6H9NO2S
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Color Off-white to yellow
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SMILES
O=C([C@H](CSCC#C)N)O
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別名
SPRC
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
H2O : 25 mg/mL (157.03 mM; Need ultrasonic)
DMSO : < 1 mg/mL (insoluble or slightly soluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (270 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Sidhapuriwala JN, et al. Effects of S-propargyl-cysteine (SPRC) in caerulein-induced acute pancreatitis in mice. PLoS One. 2012;7(3):e32574. [Content Brief]
[2]. Wen YD, et al. The Pharmacological Effects of S-Propargyl-Cysteine, a Novel Endogenous H2S-Producing Compound. Handb Exp Pharmacol. 2015;230:325-36. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 6.2810 mL | 31.4051 mL | 62.8101 mL | 157.0253 mL |
| 5 mM | 1.2562 mL | 6.2810 mL | 12.5620 mL | 31.4051 mL | |
| 10 mM | 0.6281 mL | 3.1405 mL | 6.2810 mL | 15.7025 mL | |
| 15 mM | 0.4187 mL | 2.0937 mL | 4.1873 mL | 10.4684 mL | |
| 20 mM | 0.3141 mL | 1.5703 mL | 3.1405 mL | 7.8513 mL | |
| 25 mM | 0.2512 mL | 1.2562 mL | 2.5124 mL | 6.2810 mL | |
| 30 mM | 0.2094 mL | 1.0468 mL | 2.0937 mL | 5.2342 mL | |
| 40 mM | 0.1570 mL | 0.7851 mL | 1.5703 mL | 3.9256 mL | |
| 50 mM | 0.1256 mL | 0.6281 mL | 1.2562 mL | 3.1405 mL | |
| 60 mM | 0.1047 mL | 0.5234 mL | 1.0468 mL | 2.6171 mL | |
| 80 mM | 0.0785 mL | 0.3926 mL | 0.7851 mL | 1.9628 mL | |
| 100 mM | 0.0628 mL | 0.3141 mL | 0.6281 mL | 1.5703 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
S-Propargylcysteine 関連分類
HY-W001538 関連分類
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