3262-64-4
Chemical Structure
S-Propargylcysteine
Synonym(s): SPRC
- CAS 番号: 3262-64-4
- Formula:C6H9NO2S
- Molecular Weight:159.21
IUPAC Name: S-(prop-2-yn-1-yl)-L-cysteine
InChIKey: JAKVEOCMEMGHGB-YFKPBYRVSA-N
SMILES: O=C([C@H](CSCC#C)N)O
Biological Activity: S-Propargylcysteine (SPRC), a structural analog of S-allyl cysteine (SAC), is a slow H2S-releasing compound. S-Propargylcysteine reduces Ca2+ accumulation and inflammatory cytokines, inhibits STAT3, and elevates p53 and Bax. S-Propargylcysteine has anti-inflammatory activity and protects mice against acute pancreatitis. S-Propargylcysteine also has cardioprotective, neuroprotective acitivties[1][2].
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S-Propargylcysteine | 97.0% | S-Propargylcysteine (SPRC), a structural analog of S-allyl cysteine (SAC), is a slow H2S-releasing compound. S-Propargylcysteine reduces Ca2+ accumulation and inflammatory cytokines, inhibits STAT3, and elevates p53 and Bax. S-Propargylcysteine has anti-inflammatory activity and protects mice against acute pancreatitis. S-Propargylcysteine also has cardioprotective, neuroprotective acitivties. | ||||||||||||||||||||
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- [1]. Sidhapuriwala JN, et al. Effects of S-propargyl-cysteine (SPRC) in caerulein-induced acute pancreatitis in mice. PLoS One. 2012;7(3):e32574. [Content Brief]
- [2]. Wen YD, et al. The Pharmacological Effects of S-Propargyl-Cysteine, a Novel Endogenous H2S-Producing Compound. Handb Exp Pharmacol. 2015;230:325-36. [Content Brief]
Keywords
