S-Propargylcysteine
Based on 1 Customer Validation
S-Propargylcysteine (SPRC), a structural analog of S-allyl cysteine (SAC), is a slow H2S-releasing compound. S-Propargylcysteine reduces Ca2+ accumulation and inflammatory cytokines, inhibits STAT3, and elevates p53 and Bax. S-Propargylcysteine has anti-inflammatory activity and protects mice against acute pancreatitis. S-Propargylcysteine also has cardioprotective, neuroprotective acitivties.
For research use only. We do not sell to patients.
- Purity: 97.0%
- CAS No.: 3262-64-4
- Formula: C6H9NO2S
- Molecular Weight:159.21
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 3262-64-4
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Appearance Solid
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Molecular Weight 159.21
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Formula C6H9NO2S
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Color Off-white to yellow
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SMILES
O=C([C@H](CSCC#C)N)O
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Synonyms
SPRC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : 25 mg/mL (157.03 mM; Need ultrasonic)
DMSO : < 1 mg/mL (insoluble or slightly soluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
[1]. Sidhapuriwala JN, et al. Effects of S-propargyl-cysteine (SPRC) in caerulein-induced acute pancreatitis in mice. PLoS One. 2012;7(3):e32574. [Content Brief]
[2]. Wen YD, et al. The Pharmacological Effects of S-Propargyl-Cysteine, a Novel Endogenous H2S-Producing Compound. Handb Exp Pharmacol. 2015;230:325-36. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 6.2810 mL | 31.4051 mL | 62.8101 mL | 157.0253 mL |
| 5 mM | 1.2562 mL | 6.2810 mL | 12.5620 mL | 31.4051 mL | |
| 10 mM | 0.6281 mL | 3.1405 mL | 6.2810 mL | 15.7025 mL | |
| 15 mM | 0.4187 mL | 2.0937 mL | 4.1873 mL | 10.4684 mL | |
| 20 mM | 0.3141 mL | 1.5703 mL | 3.1405 mL | 7.8513 mL | |
| 25 mM | 0.2512 mL | 1.2562 mL | 2.5124 mL | 6.2810 mL | |
| 30 mM | 0.2094 mL | 1.0468 mL | 2.0937 mL | 5.2342 mL | |
| 40 mM | 0.1570 mL | 0.7851 mL | 1.5703 mL | 3.9256 mL | |
| 50 mM | 0.1256 mL | 0.6281 mL | 1.2562 mL | 3.1405 mL | |
| 60 mM | 0.1047 mL | 0.5234 mL | 1.0468 mL | 2.6171 mL | |
| 80 mM | 0.0785 mL | 0.3926 mL | 0.7851 mL | 1.9628 mL | |
| 100 mM | 0.0628 mL | 0.3141 mL | 0.6281 mL | 1.5703 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
S-Propargylcysteine Related Classifications
HY-W001538 Related Classifications
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