Rotigotine-d7 hydrochloride
Rotigotine-d7 (N-0923-d7) hydrochloride is the deuterium labeled Rotigotine(HY-75502). Rotigotine is a potent dopamine receptor agonist with Ki values of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors and dopamine D1 receptor. Rotigotine a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor. Rotigotine can be used for parkinson's disease (PD) research.
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- 화학식: C19H19D7ClNOS
- 분자량:358.98
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Help & FAQs
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 125572-93-2
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분자량 358.98
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화학식 C19H19D7ClNOS
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SMILES
OC1=C(CC[C@H](N(C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])CCC2=CC=CS2)C3)C3=CC=C1.[H]Cl
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Synonyms
N-0923 D7 Hydrochloride
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Rotigotine-d7 hydrochloride Related Classifications
HY-A0007S Related Classifications
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