125572-93-2
Chemical Structure
Rotigotine Hydrochloride
Synonym(s): N-0923 Hydrochloride
- CAS No.: 125572-93-2
- Formula:C19H26ClNOS
- Molecular Weight:351.93
IUPAC Name: (S)-6-(propyl(2-(thiophen-2-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride
InChIKey: CEXBONHIOKGWNU-NTISSMGPSA-N
SMILES: OC1=C2CC[C@@H](CC2=CC=C1)N(CCC3=CC=CS3)CCC.[H]Cl
Biological Activity: Rotigotine Hydrochloride (N-0923 Hydrochloride) is a full agonist of dopamine receptor, a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor, with Ki of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors, and dopamine D1 receptor.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Rotigotine Hydrochloride | 99.45% | Rotigotine Hydrochloride (N-0923 Hydrochloride) is a full agonist of dopamine receptor, a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor, with Ki of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors, and dopamine D1 receptor. | ||||||||||||||||||||
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Rotigotine Hydrochloride (Standard) | ≥98% | Rotigotine (Hydrochloride) (Standard) is the analytical standard of Rotigotine (Hydrochloride). This product is intended for research and analytical applications. Rotigotine Hydrochloride (N-0923 Hydrochloride) is a full agonist of dopamine receptor, a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor, with Ki of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors, and dopamine D1 receptor. | ||||||||||||||||||||
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Rotigotine-d7 hydrochloride | Rotigotine-d7 (N-0923-d7) hydrochloride is the deuterium labeled Rotigotine(HY-75502). Rotigotine is a potent dopamine receptor agonist with Ki values of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors and dopamine D1 receptor. Rotigotine a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor. Rotigotine can be used for parkinson's disease (PD) research. | |||||||||||||||||||||
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Similarity Score 1.00
HY-15394(Rac)-Rotigotine hydrochloride -
Similarity Score 1.00
HY-Z0849A(R)-6-(Propyl(2-(thiophen-2-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride -
Similarity Score 0.98
HY-15394A(Rac)-Rotigotine -
Similarity Score 0.98
HY-75502RRotigotine (Standard) -
Similarity Score 0.89
HY-15394S1(Rac)-Rotigotine-d3 hydrochloride -
Similarity Score 0.88
HY-I0157(S)-5-Methoxy-N-propyl-N-(2-(thiophen-2-yl)ethyl)-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride -
Similarity Score 0.80
HY-1207404-Amino-PPHT -
Similarity Score 0.80
HY-W701408rac-Rotigotine-d3 methyl ether -
Similarity Score 0.76
HY-131531A5-OH-DPAT -
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