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Cat. No.: HY-149661

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PDE5-IN-11

PDE5-IN-11 is a potent inhibitor of PDE5 with an IC₅₀ of 40 nM. PDE5-IN-11 also inhibits PDE4 and PDE6 with IC₅₀s of 1.78 and 0.09 μM, respectively.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

화학식: C₂₀H₂₈N₆O₄
분자량:416.47

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

PDE5-IN-11 Chemical Structure

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

PDE5-IN-11 is a potent inhibitor of PDE5 with an IC₅₀ of 40 nM. PDE5-IN-11 also inhibits PDE4 and PDE6 with IC₅₀s of 1.78 and 0.09 μM, respectively^[1].

All Phosphodiesterase (PDE) Isoforms :

Chemical Information

분자량 416.47
화학식 C₂₀H₂₈N₆O₄
SMILES

COC1=CC=C(CNC2=C3C(N(C(C)C)C(N3)=O)=NC(N(CCO)CCO)=N2)C=C1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Jiayuan Liu, et al. Drug repurposing and structure-based discovery of new PDE4 and PDE5 inhibitors, European Journal of Medicinal Chemistry (2023).

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Other size

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Amount: USD 0.00

Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
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Purity:
수량:

PDE5-IN-11

All Phosphodiesterase (PDE) Isoforms