Schisandrol B (Standard)
Schisandrol B (Standard) is the analytical standard of Schisandrol B. This product is intended for research and analytical applications. Schisandrol B (Gomisin-A) is a major active constituent of Schisandra chinensis with hepato-protective effects. Schisandrol B inhibits reactive oxygen species (ROS) production. Schisandrol B inhibits the activity of P-glycoprotein and CYP3A and also has anti-inflammatory, anti-diabetic and antioxidant activities.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 98%
- CAS No.: 58546-54-6
- 화학식: C23H28O7
- 분자량:416.46
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 58546-54-6
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분자량 416.46
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화학식 C23H28O7
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SMILES
O[C@@]([C@@H](C)C1)(C)CC2=CC(OC)=C(OC)C(OC)=C2C3=C1C=C4OCOC4=C3OC
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Synonyms
Gomisin-A (Standard); TJN-101 (Standard); Wuweizi alcohol-B (Standard)
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Jiang Y, et al. Schisandrol B protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of liver regeneration. Toxicol Sci. 2015 Jan;143(1):107-15. [Content Brief]
[2]. Jeong-Seok Kim, et al. Gomisin A modulates aging progress via mitochondrial biogenesis in human diploid fibroblast cells. Clin Exp Pharmacol Physiol. 2018 Jun;45(6):547-555. [Content Brief]
[3]. Jin J, et al. Enhancement of oral bioavailability of paclitaxel after oral administration of Schisandrol B in rats. Biopharm Drug Dispos. 2010 May;31(4):264-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- Schisandrol B (Standard)
- 58546-54-6
- Gomisin-A (Standard)
- TJN-101 (Standard)
- Wuweizi alcohol-B (Standard)
- Reference Standards
- Reactive Oxygen Species (ROS)
- Cytochrome P450
- Autophagy
- Hepato-protective
- CYP2E1
- CYP3A11
- p53
- p21
- CCND1
- PCNA
- BCL-2
- lignan
- P-glycoprotein
- anti-inflammatory
- anti-diabetic
- antioxidant
- Inhibitor
- inhibitor
- inhibit