Val-Cit-Exatecan
Val-Cit-Exatecan is a peptide-linked anti-tumor payload that can be used for the synthesis of antibody-drug conjugates (ADC). Val-Cit-Exatecan consists of DNA TopI inhibitor Exatecan (HY-13631) and a cathepsin-cleavable ADC linker (valine-citrulline). Val-Cit-Exatecan can be used in the research of colorectal cancer, gastric cancer, breast cancer, non-small cell lung cancer, ovarian cancer, head and neck cancer, pancreatic cancer, cervical cancer, and melanoma.
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- CAS No.: 2952679-21-7
- 화학식: C38H47FN8O9
- 분자량:778.83
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Topoisomerase I |
Chemical Information
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CAS No. 2952679-21-7
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분자량 778.83
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화학식 C38H47FN8O9
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SMILES
CC(C)[C@H](N)C(N[C@@H](CCCNC(N)=O)C(NCOCC(N[C@@H]1C2=C3C(C(N4C3)=CC([C@](O)(C(OC5)=O)CC)=C5C4=O)=NC6=CC(F)=C(C)C(CC1)=C62)=O)=O)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)