1. Metabolic Enzyme/Protease
    Autophagy
  2. FXR
    Autophagy
  3. Nidufexor

Nidufexor 

Cat. No.: HY-109096 Purity: 99.83%
Handling Instructions

Nidufexor is a farnesoid X receptor (FXR) agonist.

For research use only. We do not sell to patients.

Nidufexor Chemical Structure

Nidufexor Chemical Structure

CAS No. : 1773489-72-7

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 165 In-stock
Estimated Time of Arrival: December 31
5 mg USD 150 In-stock
Estimated Time of Arrival: December 31
10 mg USD 250 In-stock
Estimated Time of Arrival: December 31
50 mg USD 750 In-stock
Estimated Time of Arrival: December 31
100 mg USD 1500 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Nidufexor is a farnesoid X receptor (FXR) agonist[1].

IC50 & Target

FXR[1]

Molecular Weight

487.93

Formula

C₂₇H₂₂ClN₃O₄

CAS No.

1773489-72-7

SMILES

CN1C(C2=CC(Cl)=CC=C2OC3)=C3C(C(N(CC4=CC=CC=C4)CC5=CC=C(C(O)=O)C=C5)=O)=N1

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 83.33 mg/mL (170.78 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0495 mL 10.2474 mL 20.4947 mL
5 mM 0.4099 mL 2.0495 mL 4.0989 mL
10 mM 0.2049 mL 1.0247 mL 2.0495 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (4.26 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (4.26 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Product Name:
Nidufexor
Cat. No.:
HY-109096
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