ARX305 Antibody
ARX305 Antibody is a high-affinity, humanized anti-CD70 antibody. ARX305 Antibody forms an antibody-drug conjugate (ADC) (ARX305) with the potent microtubule inhibitor PEG4-aminooxy-MMAF (AS269) (HY-128968). As a targeting component, ARX305 Antibody mediates the binding and internalization of ARX305 to CD70-positive tumor cells, whereas the unconjugated ARX305 Antibody exhibits only weak anti-tumor activity in various xenograft and disseminated tumor models. ARX305 Antibody can be used in the research of a variety of solid tumors and hematological malignancies.
For research use only. We do not sell to patients.
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Human IgG1 kappa (without para-acetyl phenylalanine (pAF))
Human
TNFSF7/CD27L/CD70
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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Product Image
ELISA, FACS, Functional assay
Chemical Information
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ARX305 Antibody Related Classifications
HY-P991930 Related Classifications
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