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Majoranaquinone

Majoranaquinone exhibits a high antibacterial effect against 4 Staphylococcus, 1 Moraxella, and 1 Enterococcus strains. Majoranaquinone shows substantial efflux pump inhibitory activity in Escherichia coliATCC 25922 strain. Majoranaquinone is found to be an effective biofilm formation inhibitor on E.coli, ATCC 25922 and E. coli K-12 AG100 bacteria.

For research use only. We do not sell to patients.

CAS No.: 1596355-59-7
Formula: C₁₄H₁₀O₄
Molecular Weight:242.23

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

Majoranaquinone Chemical Structure

CAS No.: 1596355-59-7

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Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

All Antibiotic Isoforms :

In Vitro

Majoranaquinone (compound 1) (0.195-100 mM 20 h) exhibits a high antibacterial effect against 4 Staphylococcus, 1 Moraxella, and 1 Enterococcus, strains^[1].
Majoranaquinone (62.5-1000 μM, 48 h) shows substantial efflux pump inhibitory activity in Escherichia coli ATCC 25922 strain^[1].
Majoranaquinone (62.5-1000 μM; 48 h) is an effective biofilm formation inhibitor in E.coli, ATCC 25922 and E. coli K-12 AG100 bacteria^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay^[1]

Cell Line:

S. aureus ATCC 25923, S. aureus MRSA ATCC 43300, S. aureus ATCC 29213, M. catarrhalis ATCC 25238, E. faecalis ATCC 29212, B. subtilis ATCC 6633
Concentration:

0.195-100 mM
Incubation Time:

20 hours
Result:

Had MIC values of 125 μM against S. aureus ATCC 25923 and 12.5 μM against S. aureus MRSA ATCC 43300, 250 μM against S. aureus ATCC 29213 and 250 μM against M. catarrhalis ATCC 25238, 1 mM against E. faecalis ATCC 29212, and 7.8 μM against B. subtilis ATCC 6633.

Chemical Information

CAS No. 1596355-59-7
Molecular Weight 242.23
Formula C₁₄H₁₀O₄
SMILES

O=C1C2=C(C(C3=C1C=CC=C3)=O)C(CO)=C(C)O2
Structure Classification
- Quinones
- Naphthalene Quinones
Initial Source
- Plants
- Labiatae
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Tasneem Sultan Abu Ghazal, et al. Furanonaphthoquinones, Diterpenes, and Flavonoids from Sweet Marjoram and Investigation of Antimicrobial, Bacterial Efflux, and Biofilm Formation Inhibitory Activities. ACS Omega. 2023 Sep 14;8(38):34816-34825.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References

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