14 Results for "

propionyl-coa

" in MedChemExpress (MCE) Product Catalog:
Products (14)

14 Results for "propionyl-coa" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-137808
CAS No.: 108347-97-3
Purity:  94%
Synonyms: Succinyl-coa sodium
Succinyl CoA (Succinyl-coenzyme A) sodium is a pivotal intermediate metabolite in the tricarboxylic acid cycle and a key coenzyme A metabolite. Succinyl CoA sodium is biosynthesized from α-ketoglutarate or propionyl-CoA. Succinyl CoA sodium acts as a critical precursor and substrate for heme biosynthesis and gluconeogenesis. Succinyl CoA sodium insufficiency caused by cobalamin deficiency is directly linked to growth retardation, impaired heme synthesis, tissue glycine accumulation and neurological abnormalities. Succinyl CoA sodium can be used in research on metabolic, neurological, and hematological abnormalities (such as porphyria) caused by nutritional vitamin B12 deficiency (leading to a lack of Succinyl-Coenzyme A synthesis) .
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Cat. No.: HY-113092
CAS No.: 17298-37-2
Purity:  ≥98.0%
Propionylcarnitine is metabolized by carnitine acetyltransferase from propionyl-CoA. Increased propionylcarnitine is regarded as a biomarker of vitamin B12 deficiency .
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Cat. No.: HY-148285
CAS No.: 604-98-8
Synonyms: Succinyl-coenzyme A; S-(Hydrogen succinyl)coenzyme A
Succinyl CoA (Succinyl-coenzyme A) is a pivotal intermediate metabolite in the tricarboxylic acid cycle and a key coenzyme A metabolite. Succinyl CoA is biosynthesized from α-ketoglutarate or propionyl-CoA. Succinyl CoA acts as a critical precursor and substrate for heme biosynthesis and gluconeogenesis. Succinyl CoA insufficiency caused by cobalamin deficiency is directly linked to growth retardation, impaired heme synthesis, tissue glycine accumulation and neurological abnormalities. Succinyl CoA can be used in research on metabolic, neurological, and hematological abnormalities (such as porphyria) caused by nutritional vitamin B12 deficiency (leading to a lack of Succinyl-Coenzyme A synthesis) .
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Cat. No.: HY-P5112A
Synonyms: Azido-PEG3-FLAG TFA
Research Areas:  

Others

Azido-PEG3-DYKDDDDK (azide-PEG3-FLAG) TFA is a multifunctional fusion tag for the purification of recombinant proteins. Azido-PEG3-DYKDDDDK TFA is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .
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Cat. No.: HY-P5112
CAS No.: 2243206-95-1
Synonyms: Azido-PEG3-FLAG
Research Areas:  

Others

Azido-PEG3-DYKDDDDK (azide-PEG3-FLAG) is a multifunctional fusion tag for the purification of recombinant proteins. Azido-PEG3-DYKDDDDK is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .
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Cat. No.: HY-164909
CAS No.: 2170608-85-0
Target:  

PANK

Research Areas:  

Metabolic Disease

PZ-3022 is an orally active allosteric agonist of pantothenate kinase (PanK) with an EC50 of 5.3 nM against PanK3. PZ-3022 antagonizes the inhibitory effect of C3-CoA. PZ-3022 increases CoA levels in cells and the liver, upregulates CoASH and C2-CoA, downregulates C3-CoA, and restores impaired TCA cycle and mitochondrial function. PZ-3022 can be used for the research of propionic acidemia and metabolic CoA deficiency .
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Cat. No.: HY-B0399A
CAS No.: 406-76-8
Synonyms: DL-Carnitine; DL-Levocarnitine
(±)-Carnitine (DL-Carnitine) is an orally effective racemic mixture of L-Carnitine (HY-B0399) and D-Carnitine. (±)-Carnitine elevates the mitochondrial NAD +/NADH ratio in the presence of 1,3-butanediol (HY-77490A). (±)-Carnitine does not increase glucose and urea production from L-glutamine, but stimulates propionate gluconeogenesis in rat renal cortical slices, and significantly reduces hepatic ketone body levels in rats fed a diet containing 30% high fat plus 20% 1,3-butanediol .
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Cat. No.: HY-141467S
CAS No.: 607721-34-6
Propionyl CoA-d5 is the deuterium labeled Propionyl CoA (HY-141467). Propionyl CoA serves as a common intermediate in the catabolic pathways of 1,2-propanediol and propionate in Salmonella enterica serovar Typhimurium LT2, and also functions as a precursor for 2-methylcitrate. Propionyl CoA is utilized as a substrate for the 2-methylcitrate synthase (PrpC) enzyme to synthesize 2-methylcitrate .
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Cat. No.: HY-CE00172
CAS No.: 920318-19-0
Research Areas:  

Others

(3,4-Dihydroxyphenyl)propionyl-CoA is a derivative of Coenzyme A (HY-128851).
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Cat. No.: HY-CE00862
Synonyms: 3-Hydroxy-3-(3-hydroxy-4-methoxyphenyl)propionyl-coenzyme A
Research Areas:  

Metabolic Disease

3-Hydroxy-3-(3-hydroxy-4-methoxyphenyl)propionyl-CoA (3-Hydroxy-3-(3-hydroxy-4-methoxyphenyl)propionyl-coenzyme A) is a coenzyme A derivative.
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Cat. No.: HY-W048444
CAS No.: 22342-46-7
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Diaminobiotin is a biotin analog. Diaminobiotin can increase the transcriptional activity of IL-2 and IL-2R genes in Jurkat cells. Diaminobiotin does not affect the abundance of holocarboxylase and the activity of propionyl-CoA carboxylase in Jurkat cells .
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Cat. No.: HY-141467S1
Propionyl CoA-d5 sodium is the deuterium labeled Propionyl CoA. Propionyl CoA serves as a common intermediate in the catabolic pathways of 1,2-propanediol and propionate in Salmonella enterica serovar Typhimurium LT2, and also functions as a precursor for 2-methylcitrate. Propionyl CoA is utilized as a substrate for the 2-methylcitrate synthase (PrpC) enzyme to synthesize 2-methylcitrate .
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Cat. No.: HY-148285A
CAS No.: 403982-65-0
Synonyms: Succinyl-coenzyme A disodium; S-(Hydrogen succinyl)coenzyme A disodium
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Succinyl CoA (Succinyl-coenzyme A) disodium is a pivotal intermediate metabolite in the tricarboxylic acid cycle and a key coenzyme A metabolite. Succinyl CoA disodium is biosynthesized from α-ketoglutarate or propionyl-CoA. Succinyl CoA disodium acts as a critical precursor and substrate for heme biosynthesis and gluconeogenesis. Succinyl CoA disodium insufficiency caused by cobalamin deficiency is directly linked to growth retardation, impaired heme synthesis, tissue glycine accumulation and neurological abnormalities. Succinyl-Coenzyme A sodium can be used in research on metabolic, neurological, and hematological abnormalities (such as porphyria) caused by nutritional vitamin B12 deficiency (leading to a lack of Succinyl-Coenzyme A synthesis) .
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