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Cat. No.: HY-132001S

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Ziftomenib-d₃

(Synonyms: KO-539-d₃)

Ziftomenib-d₃ (KO-539-d₃) is the deuterium labeled Ziftomenib (HY-132001). Ziftomenib (KO-539) is an orally active menin-MLL interaction inhibitor with antitumor activities.

For research use only. We do not sell to patients.

Formula: C₃₃H₃₉D₃F₃N₉O₂S₂
Molecular Weight:720.89

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Ziftomenib-d₃ Chemical Structure

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(In Japan)

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Biological Activity
- Description
- In Vitro
- Application
Chemical Information
Purity & Documentation
Calculators
Help & FAQs
Bioz

Biological Activity

Description

Ziftomenib-d₃ (KO-539-d₃) is the deuterium labeled Ziftomenib (HY-132001). Ziftomenib (KO-539) is an orally active menin-MLL interaction inhibitor with antitumor activities.

All Epigenetic Reader Domain Isoforms :

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled Cas 2134675-36-6
Molecular Weight 720.89
Formula C₃₃H₃₉D₃F₃N₉O₂S₂
SMILES

N#CC(N1C[C@@H](N2CCN(S(=O)(C)=O)CC2)C)=CC3=C1C=CC(CN4CCC(NC5=C(C=C(CC(F)(F)F)S6)C6=NC(NC([2H])([2H])[2H])=N5)CC4)=C3C
Synonyms

KO-539-d₃
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.