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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
110 Results for "
complement component
" in MedChemExpress (MCE) Product Catalog:
Products (110)
110 Results for "complement component" in MCE Product Catalog:
Cat. No.: HY-145720
CAS No.: 1639264-46-2
Synonyms: ALN-CC5
Research Areas:
Cemdisiran (ALN-CC5) is an N-acetylgalactosamine-conjugated RNAi agent and also a complement component C5 inhibitor. Cemdisiran targets C5 mRNA, cleaves C5 mRNA via the endogenous RNA interference pathway, and inhibits the production of C5 protein in the liver. Cemdisiran exerts a dose-dependent inhibitory effect on total C5 concentrations in cynomolgus monkeys. When used in combination with Pozelimab (HY-P99786) in cynomolgus monkeys, Cemdisiran achieves a more sustained and complete inhibitory effect on complement activity. Cemdisiran can be used in the research of paroxysmal nocturnal hemoglobinuria and other complement-mediated diseases .
Cat. No.: HY-P10633
CAS No.: 1628913-44-9
Target:
Research Areas:
Cat. No.: HY-148457
CAS No.: 1613641-69-2
Synonyms: Izervay
Target:
Research Areas:
Avacincaptad pegol (Izervay) is a selective inhibitor targeting complement component C5, and is a pegylated ribonucleic acid aptamer. Avacincaptad pegol inhibits the cleavage of C5 into pro-inflammatory C5a and C5b, which forms the membrane attack complex (C5b-9), thereby reducing inflammatory cell recruitment and retinal cell damage. Avacincaptad pegol can slow the growth of geographic atrophy (GA) lesions and reduce the risk of persistent vision loss. Avacincaptad pegol can be used in research of geographic atrophy associated with age-related macular degeneration (AMD) and has been approved by the FDA .
Cat. No.: HY-N1464A
CAS No.: 25274-27-5
Target:
Cat. No.: HY-145720A
Purity: 96.02%
Synonyms: ALN-CC5 sodium
Research Areas:
Cemdisiran sodium (ALN-CC5 sodium) is an N-acetylgalactosamine-conjugated RNAi agent and also a complement component C5 inhibitor. Cemdisiran sodium targets C5 mRNA, cleaves C5 mRNA via the endogenous RNA interference pathway, and inhibits the production of C5 protein in the liver. Cemdisiran sodium exerts a dose-dependent inhibitory effect on total C5 concentrations in cynomolgus monkeys. When used in combination with Pozelimab (HY-P99786) in cynomolgus monkeys, Cemdisiran sodium achieves a more sustained and complete inhibitory effect on complement activity. Cemdisiran sodium can be used in the research of paroxysmal nocturnal hemoglobinuria and other complement-mediated diseases .
Cat. No.: HY-P3502B
Target:
Research Areas:
Zilucoplan (PEG2) is a Zilucoplan (HY-P3502) derivative, where the linker section replaces PEG24 by PEG2. Zilucoplan is a potent complement component 5 (C5) inhibitor .
Cat. No.: HY-177621
CAS No.: 3069641-77-3
Target:
Research Areas:
Cevolisiran, a siRNA, is a complement component 3 (C3) synthesis reducer.
Cat. No.: HY-177621A
Target:
Research Areas:
Cevolisiran sodium, a siRNA, is a complement component 3 (C3) synthesis reducer.
Cat. No.: HY-N7401
CAS No.: 138916-58-2
Target:
Cat. No.: HY-P3502A
Synonyms: RA101495 TFA; RA3193 TFA
Target:
Research Areas:
Cat. No.: HY-P99886
CAS No.: 219685-93-5
Synonyms: h5G1. 1-SC
Target:
Research Areas:
Cat. No.: HY-P5528
Cat. No.: HY-P85894
Synonyms: C3 binding protein; C3b/C4b receptor; C3BR; C4BR; CD 35; CD35; CD35 antigen; complement component; 3b/4b; receptor 1; Knops blood group; complement component; 3b/4b; receptor 1 including Knops blood group system; complement component receptor 1; complement receptor 1; complement receptor type 1; CR 1; CR1; CR1_HUMAN; KN; Knops blood group antigen
Cat. No.: HY-P74371A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C7; complement component C7; complement C7; complement component 7
Cat. No.: HY-P705312
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C9; complement component 9; complement C9; ARMD15; complement component C9; C9D
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
