219685-93-5
219685-93-5
Chemical Structure
Pexelizumab
Synonym(s): h5G1. 1-SC
- CAS No.: 219685-93-5
- Formula:N/A
- Molecular Weight:(26.271 kDa)
IUPAC Name: 4-fluoro-2-methyl-6-(trifluoromethyl)aniline
SMILES: [Pexelizumab]
Biological Activity: Pexelizumab (h5G1. 1-SC) is a humanized scFv monoclonal antibody directed against the C5 complement component. Pexelizumab inhibits apoptosis and leukocyte infiltration. Pexelizumab can be used for the research of cerebral IR injury and myocardial infarction[1][2].
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Pexelizumab | 99.0% | Pexelizumab (h5G1. 1-SC) is a humanized scFv monoclonal antibody directed against the C5 complement component. Pexelizumab inhibits apoptosis and leukocyte infiltration. Pexelizumab can be used for the research of cerebral IR injury and myocardial infarction. | ||||||||||||||||||||
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References
- [1]. APEX AMI Investigators, et al. Pexelizumab for acute ST-elevation myocardial infarction in patients undergoing primary percutaneous coronary intervention: a randomized controlled trial. JAMA. 2007 Jan 3;297(1):43-51. [Content Brief]
- [2]. Thomas TC, et al. Inhibition of complement activity by humanized anti-C5 antibody and single-chain Fv. Mol Immunol. 1996 Dec;33(17-18):1389-401. [Content Brief]
Keywords
