207 Results for "

Fluorogenic substrate

" in MedChemExpress (MCE) Product Catalog:
Products (207)

207 Results for "Fluorogenic substrate" in MCE Product Catalog:

Art. -Nr.: HY-P4310
CAS. Nr.: 73554-84-4
Target:  

Ser/Thr Protease

Forschungsgebiete:  

Others

Boc-Val-Leu-Lys-AMC is a sensitive, fluorogenic, and specific substrate of plasmin, as well as acrosin from the ascidian Halocynthia roretzi, porcine calpain isozymes I and II, and papain .
loading...
    loading...
Art. -Nr.: HY-137164A
CAS. Nr.: 62037-42-7
Target:  

Fluorescent Dye

Forschungsgebiete:  

Others

Ala-Ala-Phe-AMC TFA is the TFA salt form for Ala-Ala-Phe-AMC. Ala-Ala-Phe-AMC TFA is a fluorogenic substrate, which is used to for tripeptidyl peptidase II (TPPII) activity determination .
loading...
    loading...
Art. -Nr.: HY-P4341
CAS. Nr.: 152881-17-9
Target:  

PAI-1 Fluorescent Dye

Forschungsgebiete:  

Others

D-Val-Leu-Lys-AMC is a selective fluorogenic peptide substrate of plasmin. D-Val-Leu-Lys-AMC can be used for the quantification of enzymatic activity of plasmin. Ex: 360-380 nm, Em: 440-460 nm .
loading...
    loading...
Art. -Nr.: HY-P11715
CAS. Nr.: 960607-97-0
Target:  

Fluorescent Dye

Forschungsgebiete:  

Neurological Disease

Abz-GFDPFRQ-EDDnp is a fluorogenic substrate for metallothionein oligopeptidase (λex=320 nm, λem=420 nm). Abz-GFDPFRQ-EDDnp is used to determine the enzymatic activity of metallothionein oligopeptidase in tissue extracts and for research on temporal lobe epilepsy .
loading...
    loading...
Art. -Nr.: HY-137337
CAS. Nr.: 71973-79-0
Reinheit:  99.89%
Target:  

Fluorescent Dye

Forschungsgebiete:  

Others

Suc-Ala-Ala-Phe-AMC is a fluorogenic chymotrypsin substrate, can be hydrolyzed by endopeptidase. Suc-Ala-Ala-Phe-AMC has been used in both in vivo assays of the acrosome reaction and in vitro enzyme assays .
loading...
    loading...
Art. -Nr.: HY-137838
CAS. Nr.: 94099-57-7
Forschungsgebiete:  

Infection

H-Tyr-AMC is a fluorogenic substrate for tyrosine aminopeptidases. H-Tyr-AMC is an inhibitor of tobacco and potato hydroxycinnamoyl-CoA:tyramine N-(hydroxycinnamoyl)transferase (THT) with Ki values of 0.72 μM (tobacco) and 0.42 μM (potato) .
loading...
    loading...
Art. -Nr.: HY-P4341A
Target:  

PAI-1 Fluorescent Dye

Forschungsgebiete:  

Others

D-Val-Leu-Lys-AMC TFA is a selective fluorogenic peptide substrate of plasmin. D-Val-Leu-Lys-AMC TFA can be used for the quantification of enzymatic activity of plasmin. Ex: 360-380 nm, Em: 440-460 nm .
loading...
    loading...
Art. -Nr.: HY-P4331
CAS. Nr.: 113865-85-3
Forschungsgebiete:  

Cardiovascular Disease

Boc-Gln-Gly-Arg-AMC is a fluorogenic substrate for kallikrein (PKa), coagulation factor XIIa (FXIIa) and coagulation factor XIa (FXIa). Boc-Gln-Gly-Arg-AMC enables fluorescence-based activity assays for PKa, FXIIa and FXIa .
loading...
    loading...
Art. -Nr.: HY-P5123
Target:  

Angiotensin Receptor

Forschungsgebiete:  

Others

Arg-Glu(edans)-Ile-His-Pro-Phe-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(dabcyl)-Ar is a fluorogenic renin substrate  based on the N-terminal tetradecapeptide sequence of human angiotensinogen (hTDP) .
loading...
    loading...
Art. -Nr.: HY-P5123A
Target:  

Angiotensin Receptor

Forschungsgebiete:  

Others

Arg-Glu(edans)-Ile-His-Pro-Phe-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(dabcyl)-Ar TFA is a fluorogenic renin substrate  based on the N-terminal tetradecapeptide sequence of human angiotensinogen (hTDP) .
loading...
    loading...
Art. -Nr.: HY-P5202
CAS. Nr.: 104086-87-5
Forschungsgebiete:  

Others

H-Gly-Gly-Arg-AMC is a fluorogenic peptidyl-AMC substrate containing C-terminal 7-amino-4-methylcoumarin (AMC). H-Gly-Gly-Arg-AMC is a suitable for monitoring continuous thrombin generation (TGT) .
loading...
    loading...
Art. -Nr.: HY-P1986
CAS. Nr.: 1135416-11-3
Target:  

Caspase

Forschungsgebiete:  

Cancer

Z-DEVD-AFC is a cell-permeant substrate for caspase-3, which causes a shift in fluorescence uponcleavage of the AFC fluorophore. Z-DEVD-AFC can be used to detect caspase-3-like enzymes activity .
loading...
    loading...
Art. -Nr.: HY-131127
CAS. Nr.: 7270-83-9
Synonyms: AMQI
Target:  

Cholinesterase (ChE)

Forschungsgebiete:  

Others

7-Acetoxy-1-methylquinolinium iodide (AMQI) is a fluorogenic substrate for cholinesterase (Ex = 320 nm, Em = 410 nm). Hydrolysis of 7-acetoxy-1-methylquinolinium iodide is used at the fluorometric flow system for the detection and identification of inhibitors. .
loading...
    loading...
Art. -Nr.: HY-P1169A
Target:  

Caspase

Forschungsgebiete:  

Others

Ac-IETD-AFC TFA is a synthetic fluorogenic substrate that can be used to specifically detect caspase-8 activity. INDO 1 pentasodium is imbued with the fluorophore AFC (7-amino-4-trifluoromethylcoumarin). When caspase-8 recognizes and cleaves the amide bond following the IETD sequence in this substrate, AFC is released and emits fluorescence (Ex = ~400 nm; Em = ~505 nm) .
loading...
    loading...
Art. -Nr.: HY-135070
CAS. Nr.: 929903-87-7
Synonyms: Ac-Arg-Leu-Arg-AMC
Target:  

Proteasome

Forschungsgebiete:  

Others

Ac-RLR-AMC (Ac-Arg-Leu-Arg-AMC) is a fluorogenic substrate for the 26S proteasome (Ex/Em: 380/440-460 nm). AMC is released upon cleavage, and its fluorescence can be used to quantify the trypsin-like activity of 26S proteasomes .
loading...
    loading...
Art. -Nr.: HY-P5415
CAS. Nr.: 127134-13-8
Target:  

HIV

Forschungsgebiete:  

Others

DABCYL-GABA-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS is a biological active peptide. (DABCYL-GABA-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS is also called HIV protease substrate I in some literature. It is widely used for the continuous assay for HIV protease activity. The 11-Kd protease (PR) encoded by the human immunodeficiency virus 1 (HIV-1) is essential for the correct processing of viral polyproteins and the maturation of infectious virus, and is therefore a target for the design of selective acquired immunodeficiency syndrome (AIDS) therapeutics. The FRET-based fluorogenic substrate is derived from a natural processing site for HIV-1 PR. Incubation of recombinant HIV-1 PR with the fluorogenic substrate resulted in specific cleavage at the Tyr-Pro bond and a time-dependent increase in fluorescence intensity that is linearly related to the extent of substrate hydrolysis. The fluorescence quantum yields of the HIV-1 PR substrate in the FRET assay increased by 40.0- and 34.4-fold, respectively, per mole of substrate cleaved. Because of its simplicity and precision in the determination of reaction rates required for kinetic analysis, this substrate offers many advantages over the commonly used HPLC or electrophoresis-based assays for peptide substrate hydrolysis by retroviral PRs. Abs/Em = 340nm/490nm.)
loading...
    loading...
Art. -Nr.: HY-135070B
Synonyms: Ac-Arg-Leu-Arg-AMC TFA
Target:  

Proteasome

Forschungsgebiete:  

Others

Ac-RLR-AMC (Ac-Arg-Leu-Arg-AMC) TFA is a fluorogenic substrate for the 26S proteasome (Ex/Em: 380/440-460 nm). AMC is released upon cleavage, and its fluorescence can be used to quantify the trypsin-like activity of 26S proteasomes .
loading...
    loading...
Art. -Nr.: HY-D1652
CAS. Nr.: 292633-16-0
Target:  

Caspase

Forschungsgebiete:  

Others

Ac-LEHD-AMC is a fluorogenic substrate for caspase-9 (Excitation: 341 nm; Emission: 441 nm). Caspase-9 can induce hydrolysis of Ac-LEHD-AMC, resulting in the release of AMC fluorophore and its fluorescence can be used to quantify caspase-9 activity .
loading...
    loading...
Art. -Nr.: HY-P3110
CAS. Nr.: 958001-92-8
Target:  

Fluorescent Dye

Forschungsgebiete:  

Others

Ac-WLA-AMC is a fluorogenic substrate of caspase-3. Ac-WLA-AMC is cleaved to release the fluorescent moiety 7-amino-4-methylcoumarin (AMC), which can be used to quantify the β5c subunit activity .
loading...
    loading...
Art. -Nr.: HY-P4931A
CAS. Nr.: 1392300-20-7
Target:  

Fluorescent Dye

Forschungsgebiete:  

Others

Mca-KPLGL-Dap(Dnp)-AR-NH2 TFA is a fluorogenic substrate for matrix metalloproteinases (MMPs). 7-methoxycoumarin-4 acetyl (Mac) is released and its fluorescence can be used to quantify MMP activity. Mac displays Ex/Em of 328/420 nm .
loading...
    loading...