73554-84-4
Chemical Structure
Boc-Val-Leu-Lys-AMC
- CAS No.: 73554-84-4
- Formula:C32H49N5O7
- Molecular Weight:615.76
InChIKey: KVLPXRKIIFWZLM-DPZBCOQUSA-N
SMILES: CC(C1=CC=C(NC([C@H](CCCCN)NC([C@H](CC(C)C)NC([C@H](C(C)C)NC(OC(C)(C)C)=O)=O)=O)=O)C=C1O2)=CC2=O
Biological Activity: Boc-Val-Leu-Lys-AMC is a sensitive, fluorogenic, and specific substrate of plasmin, as well as acrosin from the ascidian Halocynthia roretzi, porcine calpain isozymes I and II, and papain[1][2][3][4].
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Boc-Val-Leu-Lys-AMC | 99.91% | Boc-Val-Leu-Lys-AMC is a sensitive, fluorogenic, and specific substrate of plasmin, as well as acrosin from the ascidian Halocynthia roretzi, porcine calpain isozymes I and II, and papain. | ||||||||||||||||||||
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- [1]. T Sasaki, et al. Comparative specificity and kinetic studies on porcine calpain I and calpain II with naturally occurring peptides and synthetic fluorogenic substrates. J Biol Chem. 1984 Oct 25;259(20):12489-94. [Content Brief]
- [2]. R E Smith, et al. Direct photometric or fluorometric assay of proteinases using substrates containing 7-amino-4-trifluoromethylcoumarin. Thromb Res. 1980 Feb;17(3-4):393-402. [Content Brief]
- [3]. H Kato, et al. New fluorogenic peptide substrates for plasmin. J Biochem. 1980 Jul;88(1):183-90. [Content Brief]
Keywords