Ac-LEHD-AMC
Based on 1 Customer Validation
Ac-LEHD-AMC is a fluorogenic substrate for caspase-9 (Excitation: 341 nm; Emission: 441 nm). Caspase-9 can induce hydrolysis of Ac-LEHD-AMC, resulting in the release of AMC fluorophore and its fluorescence can be used to quantify caspase-9 activity.
For research use only. We do not sell to patients.
- Purity: 98.96%
- CAS No.: 292633-16-0
- Formula: C33H41N7O11
- Molecular Weight:711.72
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Storage:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 292633-16-0
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Appearance Solid
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Molecular Weight 711.72
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Formula C33H41N7O11
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Color White to off-white
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SMILES
CC(C1=CC=C(NC([C@H](CC(O)=O)NC([C@@H](NC([C@H](CCC(O)=O)NC([C@@H](NC(C)=O)CC(C)C)=O)=O)CC2=CN=CN2)=O)=O)C=C1O3)=CC3=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 250 mg/mL (351.26 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.4050 mL | 7.0252 mL | 14.0505 mL | 35.1262 mL |
| 5 mM | 0.2810 mL | 1.4050 mL | 2.8101 mL | 7.0252 mL | |
| 10 mM | 0.1405 mL | 0.7025 mL | 1.4050 mL | 3.5126 mL | |
| 15 mM | 0.0937 mL | 0.4683 mL | 0.9367 mL | 2.3417 mL | |
| 20 mM | 0.0703 mL | 0.3513 mL | 0.7025 mL | 1.7563 mL | |
| 25 mM | 0.0562 mL | 0.2810 mL | 0.5620 mL | 1.4050 mL | |
| 30 mM | 0.0468 mL | 0.2342 mL | 0.4683 mL | 1.1709 mL | |
| 40 mM | 0.0351 mL | 0.1756 mL | 0.3513 mL | 0.8782 mL | |
| 50 mM | 0.0281 mL | 0.1405 mL | 0.2810 mL | 0.7025 mL | |
| 60 mM | 0.0234 mL | 0.1171 mL | 0.2342 mL | 0.5854 mL | |
| 80 mM | 0.0176 mL | 0.0878 mL | 0.1756 mL | 0.4391 mL | |
| 100 mM | 0.0141 mL | 0.0703 mL | 0.1405 mL | 0.3513 mL |
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