Boc-Gln-Gly-Arg-AMC
Based on 1 Customer Validation
Boc-Gln-Gly-Arg-AMC is a fluorogenic substrate for kallikrein (PKa), coagulation factor XIIa (FXIIa) and coagulation factor XIa (FXIa). Boc-Gln-Gly-Arg-AMC enables fluorescence-based activity assays for PKa, FXIIa and FXIa.
For research use only. We do not sell to patients.
- Purity: 99.77%
- CAS No.: 113865-85-3
- Formula: C28H40N8O8
- Molecular Weight:616.67
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Boc-Gln-Gly-Arg-AMC (100 μM; 150 minutes) detects FXIIa activity generated by RBC-MVs incubated with purified human FXII over 150 minutes via substrate cleavage-induced fluorescence[1].
Boc-Gln-Gly-Arg-AMC (100 μM; 150 minutes) detects PKa activity generated by RBC-MVs incubated with purified human PK and HK over 150 minutes via substrate cleavage-induced fluorescence[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 113865-85-3
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Appearance Solid
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Molecular Weight 616.67
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Formula C28H40N8O8
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Color White to off-white
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Sequence
{Boc-Gln}-Gly-{Arg-AMC}
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Sequence Shortening
{Boc-Gln}-G-{Arg-AMC}
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (162.16 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6216 mL | 8.1081 mL | 16.2161 mL | 40.5403 mL |
| 5 mM | 0.3243 mL | 1.6216 mL | 3.2432 mL | 8.1081 mL | |
| 10 mM | 0.1622 mL | 0.8108 mL | 1.6216 mL | 4.0540 mL | |
| 15 mM | 0.1081 mL | 0.5405 mL | 1.0811 mL | 2.7027 mL | |
| 20 mM | 0.0811 mL | 0.4054 mL | 0.8108 mL | 2.0270 mL | |
| 25 mM | 0.0649 mL | 0.3243 mL | 0.6486 mL | 1.6216 mL | |
| 30 mM | 0.0541 mL | 0.2703 mL | 0.5405 mL | 1.3513 mL | |
| 40 mM | 0.0405 mL | 0.2027 mL | 0.4054 mL | 1.0135 mL | |
| 50 mM | 0.0324 mL | 0.1622 mL | 0.3243 mL | 0.8108 mL | |
| 60 mM | 0.0270 mL | 0.1351 mL | 0.2703 mL | 0.6757 mL | |
| 80 mM | 0.0203 mL | 0.1014 mL | 0.2027 mL | 0.5068 mL | |
| 100 mM | 0.0162 mL | 0.0811 mL | 0.1622 mL | 0.4054 mL |
Boc-Gln-Gly-Arg-AMC Related Classifications
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