Search Result

Results for "

10A

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) Adenosine Receptor (1) Aldose Reductase (1) Apoptosis (4) Bacterial (1) Biochemical Assay Reagents (3) Caspase (1) CD3 (1) Collagen (1) COX (1) CRFR (1) DNA/RNA Synthesis (2) Drug Derivative (1) Drug-Linker Conjugates for ADC (1) EGFR (2) Environmental Pollutants (2) Estrogen Receptor/ERR (1) FXR (1) Glutaminase (1) Histone Methyltransferase (1) HSP (2) IFNAR (1) iGluR (2) IKK (1) Interleukin Related (2) Isotope-Labeled Compounds (3) mAChR (2) MDM-2/p53 (1) MicroRNA (8) Microtubule/Tubulin (2) Mitochondrial Metabolism (1) MMP (1) mRNA (1) Opioid Receptor (1) PARP (1) PD-1/PD-L1 (1) PDK-1 (1) Phosphodiesterase (PDE) (25) PI3K (1) PKA (1) Potassium Channel (3) Pyruvate Kinase (1) Reactive Oxygen Species (ROS) (3) Ser/Thr Protease (2) Small Interfering RNA (siRNA) (29) STING (1) Thyroid Hormone Receptor (1) TNF Receptor (1) Transmembrane Glycoprotein (2)
By Research Areas:	Cancer (32) Cardiovascular Disease (5) Endocrinology (1) Infection (2) Inflammation/Immunology (9) Metabolic Disease (5) Neurological Disease (19)
Oligonucleotides:	miRNA mimics (2) miRNA antagomirs (2) miRNA agomirs (2) MicroRNAs (8) Rat Pre-designed siRNA Sets (6) mRNA (1) Mouse Pre-designed siRNA Sets (6) miRNA inhibitors (2) Human Pre-designed siRNA Sets (17) Gene Editing (1) siRNAs (29)

106

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-R00059

*hsa-miR-10a-5p mimic*	MicroRNA	Cancer
hsa-miR-10a-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-10a-5p mimic hsa-miR-10a-5p mimic

HY-W116007

Octamethylcyclotetrasiloxane	Environmental Pollutants DNA/RNA Synthesis	Endocrinology
Octamethylcyclotetrasiloxane promotes the anchorage-independent growth of MCF-10A and MCF-10F cells. Octamethylcyclotetrasiloxane induces DNA damage, inhibits the expression of DNA-repairing protein BRCA1 under long-term and high-concentration exposure. Octamethylcyclotetrasiloxane exhibits intrinsic estrogenic activity .

HY-144666

GLS-1-IN-1	Glutaminase	Cancer
GLS-1-IN-1 (compound 1d) is a GLS-1 inhibitor. GLS-1-IN-1 shows inhibitory effect against Hep G2, MCF 7, and MCF 10A cells .

HY-147028

M4 mAChR agonist-1	mAChR	Neurological Disease
M4 mAChR agonist-1 (compound 10a) is a potent M4 mAChR agonist with an EC₅₀ >10 μM for human M4 .

HY-176976

Exatecan-mpGNNG	Drug-Linker Conjugates for ADC	Cancer
Exatecan-mpGNNG (Compound 10a) is the linker-payload component of an antibody-drug conjugate (ADC). Exatecan-mpGNNG is composed of Exatecan (HY-13631), a potent topoisomerase I inhibitor, and the linker .

HY-127024A

TR antagonist 2	Thyroid Hormone Receptor	Metabolic Disease
TR antagonist 2 (Compound 10a) is a competitive thyroid hormone receptors (TRα/β) antagonist (IC₅₀=47 nM). TR antagonist 2 competes with triiodothyronine (T₃) for binding to the ligand-binding domain of TR to block receptor-coactivator complex formation and inhibit target gene transcription, reducing thyroid hormone-mediated hypermetabolic effects. TR antagonist 2 is promising for research of hyperthyroidism (e.g., Graves' disease) and thyrotoxicosis .

HY-135848

N-Methylbenzamide	Phosphodiesterase (PDE)	Cancer
N-Methylbenzamide is a potent phosphodiesterase 10A (PDE10A) inhibitor. N-Methylbenzamide has anti-cancer activity .

HY-18078

PQ-10	Phosphodiesterase (PDE)	Neurological Disease
PQ-10 is a potent inhibitor of Phosphodiesterase 10A (PDE10A) with IC₅₀ andED₅₀ of 4.6 nM and 13 mg/kg, respectively. PQ-10 induces patterns of brain glucose metabolism which can be a potential translational biomarker. PQ-10 has the potential for researching psychiatric disorders like schizophrenia .

HY-117604

THPP-1 1 Publications Verification	Phosphodiesterase (PDE)	Neurological Disease
THPP-1, a SGC chemical probe, is a potent and orally bioavailable phosphodiesterase 10A (PDE10A) inhibitor, with K_i values of 1 nM and 1.3 nM for human and rat PDE10A, respectively. THPP-1 has excellent pharmacokinetic properties in preclinical species .

HY-151959

FXR agonist 4	FXR	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
FXR agonist 4 (compound 10a) is an agonist of farnesoid X receptor (FXR) with an EC₅₀ value of 1.05 μM. FXR agonist 4 effectively improves hyperlipidemia, hepatic steatosis, insulin resistance and hepatic inflammation in DIO mice. FXR agonist 4 can be used for the research of non-alcoholic fatty liver disease (NAFLD) .

HY-RI00059

*hsa-miR-10a-5p inhibitor*	MicroRNA	Cancer
hsa-miR-10a-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-10a-5p inhibitor hsa-miR-10a-5p inhibitor

HY-12913

AMG 579	Phosphodiesterase (PDE)	Neurological Disease
AMG 579 is a potent, selective, and efficacious inhibitor of phosphodiesterase 10A (PDE10A) with an IC₅₀ of 0.1 nM.

HY-152838

Gemlapodect RO554965	Phosphodiesterase (PDE)	Neurological Disease
Gemlapodect (RO554965) is an inhibitor of phosphodiesterase 10A (PDE10A). Gemlapodect can be used for researching schizophrenia .

HY-148954

PBF-999	Adenosine Receptor Phosphodiesterase (PDE)	Cancer
PBF-999 is a phosphodiesterase10A (PDE-10A) and adenosine A2A receptor (A2AR) dual antagonist.

HY-153168

Bemoradan	Phosphodiesterase (PDE)	Cardiovascular Disease
Bemoradan (compound 10a) is an orally active and selective canine Phosphodiesterase (PDE) fraction III inhibitor. Bemoradan is a long-acting, potent, inotropic vasodilator and a novel cardiotonic agent, and can be used in congestive heart failure research .

HY-149431

NDNA4	HSP Potassium Channel	Cancer
NDNA4 (compound 17) is a selective inhibitor of Hsp90α (IC₅₀: 0.34 μM). NDNA4 is a permanently charged analog with low membrane permeability and low cytotoxicity against Ovcar-8 and MCF-10A ((IC₅₀ >100 μM)). NDNA4 prevents disruption of hERG channel maturation without generating a heat shock response or causing degradation of Hsp90α-dependent client proteins .

HY-RS18435

Clec10a Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Clec10a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Clec10a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Clec10a Mouse Pre-designed siRNA Set A Clec10a Mouse Pre-designed siRNA Set A

HY-RS15828

WNT10A Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
WNT10A Human Pre-designed siRNA Set A contains three designed siRNAs for WNT10A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

WNT10A Human Pre-designed siRNA Set A WNT10A Human Pre-designed siRNA Set A

HY-178987

BJH-86	Mitochondrial Metabolism Phosphodiesterase (PDE)	Cancer
BJH-86 is a soluble mitochondrial complex 1 inhibitor (oxygen consumption rate inhibition IC₅₀ = 5 μM). BJH-86 exhibits weak inhibitory activity against phosphodiesterase 10A (PDE10A) (IC₅₀ >10 μM). BJH-86 can reduce cellular oxygen consumption and inhibit cancer cell proliferation. BJH-86 can be used for the research of cancer, such as lung cancer .

HY-178440

EGFR/COX-2-IN-2	EGFR COX Apoptosis	Inflammation/Immunology Cancer
EGFR/COX-2-IN-2 (Compound 10a) is a dual inhibitor targeting epidermal growth factor receptor (EGFR) (IC₅₀= 6.0 μM) and cyclooxygenase-2 (COX-2) (IC₅₀=50 μM). EGFR/COX-2-IN-2 induces S-phase cell cycle arrest and apoptosis. EGFR/COX-2-IN-2 is promising for research of cancers and inflammation-related diseases .

HY-178951

STING-IN-17	STING IKK Reactive Oxygen Species (ROS) IFNAR PARP Caspase	Inflammation/Immunology
STING-IN-17 (compound 10a) is an orally active STING (human STING IC₅₀ = 29 nM, mouse STING IC₅₀ = 15 nM) inhibitor. STING-IN-17 can inhibit the phosphorylation of STING, TBK1 and IRF3. STING-IN-17 dose dependently inhibits the mRNA expression of IP10, IFNB1 and ISG56. STING-IN-17 can reduce ROS and inhibit the expression of cleaved-PARP/caspase-3. STING-IN-17 can improve kidney function. STING-IN-17 can be used for research on inflammatory conditions such as acute kidney injury .

HY-E70897

*Xylanase 10A, Cellvibrio japonicus*	Biochemical Assay Reagents	Metabolic Disease
Xylanase 10A, Cellvibrio japonicus (EC 3.2.1.8) is the name given to a class of enzymes which degrade the linear polysaccharide beta-1,4-xylan into xylose, thus breaking down hemicellulose, one of the major components of plant cell walls.

HY-123743

JNJ-42314415	Phosphodiesterase (PDE)	Neurological Disease
JNJ-42314415 is a centrally active phosphodiesterase 10A (PDE10A) inhibitor, with K_i values of 35 nM and 64 nM for human recombinant PDE10A and rPDE10A, respectively .

HY-158237

PDE10A-IN-3	Phosphodiesterase (PDE)	Neurological Disease
PDE10A-IN-3 (Compound 8a) is an inhibitor of phosphodiesterase 10A (PDE10A). PDE10A-IN-3 can be used in schizophrenia research .

HY-R00058

*hsa-miR-10a-3p mimic*	MicroRNA	Cancer
hsa-miR-10a-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-10a-3p mimic hsa-miR-10a-3p mimic

HY-160111

PDM-042	Phosphodiesterase (PDE)	Neurological Disease
PDM-042 is a potent, selective, and orally active phosphodiesterase 10A (PDE10A) inhibitor. PDM-042 shows potent inhibitory activities for human and rat PDE10A with IC₅₀ values of less than 1 nM and more than 1000-fold selectivity against other phosphodiesterases. PDM-042 can be used for the research of schizophrenia .

HY-128349

MT-3014	Phosphodiesterase (PDE)	Neurological Disease
MT-3014 is a potent, highly selective and brain-penetrated phosphodiesterase 10A (PDE 10A) inhibitor, with IC₅₀s of 0.062 nM and 0.09 nM for human PDE 10A and bovine PDE 10A, respectively .

HY-P99619

Finotonlimab SCT-I10A	PD-1/PD-L1	Cancer
Finotonlimab (SCT-I10A) is a recombinant humanised IgG PD-1 antibody. Finotonlimab has the potential for solid tumors or lymphomas research .

HY-P991111

*Anti-Mouse TIGIT Antibody (10A7)*	Transmembrane Glycoprotein	Inflammation/Immunology
Anti-Mouse TIGIT Antibody (10A7) is a mouse IgG2 monoclonal antibody that targets TIGIT. Recommend Isotype Controls: Mouse IgG2a kappa, Isotype Control (HY-P99978).

HY-131973

PDE10A-IN-2 hydrochloride	Phosphodiesterase (PDE)	Cardiovascular Disease Metabolic Disease
PDE10A-IN-2 hydrochloride is a potent, highly selective and orally active phosphodiesterase 10A (PDE10A) inhibitor with an IC₅₀ of 2.8 nM. PDE10A-IN-2 hydrochloride shows selectivity of >3500-fold against other PDE subtypes. PDE10A-IN-2 hydrochloride can be used for pulmonary arterial hypertension (PAH) research .

HY-174499

Cas9 Nickase D10A mRNA (5moU)	mRNA	Others
Cas9 Nickase D10A mRNA expresses a version of the Streptococcus pyogenes SF370 Cas9 protein (CRISPR Associated Protein 9) that contains a D10A amino acid substitution. This mRNA also contains a C-terminal nuclear localization signal followed by a HA tag.Cas9 functions as part of the CRISPR (clustered regularly interspaced short palindromic repeats) genome editing system. In the CRISPR system, an RNA guide sequence targets the site of interest and the Cas9 protein is employed to perform the DNA cleavage. While wild-type Cas9 creates a double-stranded break at the target site, Cas9 nickase creates a single-stranded break. This favors homology-directed repair and decreases the occurrence of non-homologous end joining.

HY-173360

PDE10A-IN-5	Phosphodiesterase (PDE)	Cardiovascular Disease
PDE10A-IN-5 (Compound A30) is an inhibitor of phosphodiesterase 10A (PDE10A) with oral activity, and its IC₅₀ value is 3.5 nM. PDE10A-IN-5 exerts the activity of inhibiting pulmonary vascular remodeling by inhibiting *PDE10A* and activating the cyclic adenosine monophosphate (cAMP)-associated signaling pathway, and can be used for research in the field of pulmonary arterial hypertension .

HY-166876S

Nicergoline impurity 18-d4	Isotope-Labeled Compounds	Others
Nicergoline impurity 18-d₄ is deuterium labeled ((6aR,9R,10aS)-10a-Methoxy-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methanol (Nicergoline Impurity) .

HY-168064

EGFR-IN-124	EGFR	Cancer
EGFR-IN-124 (compound 10A) is an EGFR inhibitor, with IC₅₀ of 0.54 μM. EGFR-IN-124 can be used in anti-cancer research .

HY-RI00058A

*hsa-miR-10a-3p antagomir*	MicroRNA	Cancer
hsa-miR-10a-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-10a-3p antagomir hsa-miR-10a-3p antagomir

HY-146652

UGM-IN-3	Bacterial	Infection
UGM-IN-3 (compound 10a) is a UDP-galactopyranose mutase (UGM) inhibitor with a K_d of 66 μM. UGM-IN-3 inhibits the growth of *Mycobacterium tuberculosis* with a MIC value of 6.2 μg/mL .

HY-117838

Phosphodiesterase 10-IN-2	Phosphodiesterase (PDE)	Neurological Disease
Phosphodiesterase 10-IN-2 (THPP-4) is an oral active phosphodiesterase 10A (PDE10A) inhibitor with the K_i of 4.5 nM. Phosphodiesterase 10-IN-2 can be used for study of schizophrenia .

HY-18037

AMG-7980	Phosphodiesterase (PDE)	Others
AMG-7980 exhibits high affinity to phosphodiesterase 10A (PDE10A), with a K_D of 0.94 nM. AMG-7980 can be used as a tracer of PDE10A, when labeled with radioactive isotope .

HY-N10922

*(3S,4aS,10aS)-3-(Acetyloxy)-2,3,4,4a,10,10a-hexahydro-6-hydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-9(1H)-phenanthrenone*	Others	Cancer
(3S,4aS,10aS)-3-(Acetyloxy)-2,3,4,4a,10,10a-hexahydro-6-hydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-9(1H)-phenanthrenone (compound 3), a Palmitate, can be isolated from the root tissue of Salvia miltiorrhiza. (3S,4aS,10aS)-3-(Acetyloxy)-2,3,4,4a,10,10a-hexahydro-6-hydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-9(1H)-phenanthrenone (compound 3) shows anti-cancer activity against human cancer cell lines with DC₅₀s of 25.5 μg/mL (HeLa), 37.5 μg/mL (HepG2), 30.2 μg/mL (OVCAR-3), respectively .

HY-139035

CRHR1 antagonist 1	CRFR	Neurological Disease
CRHR1 antagonist 1 (compound 10a) is a non-peptide corticotropin-releasing hormone type 1 receptor (CRHR1) antagonist. CRHR1 antagonist 1 can be utilized in mental disorders research .

HY-162758

ALR2-IN-5	Aldose Reductase	Metabolic Disease
ALR2-IN-5 (Compound 10a) is an inhibitor of ALR2 with an IC₅₀ value of 99.29 nM. ALR2-IN-5 exhibits hypoglycemic effects and can be utilized in research related to diabetes .

HY-155185A

NMDA receptor antagonist 8	iGluR	Neurological Disease
NMDA receptor antagonist 8 (Compound (R)-10a) is GluN2B subunit-selective NMDA Receptor antagonist, with an K_i of 265 nM and an IC₅₀ of 62 nM. NMDA receptor antagonist 8 can be used for research of neurodegenerative diseases .

HY-155185

NMDA receptor antagonist 7	iGluR	Neurological Disease
NMDA receptor antagonist 7 (Compound (S)-10a) is GluN2B subunit-selective NMDA Receptor antagonist, with an K_i of 93 nM and an IC₅₀ of 72 nM. NMDA receptor antagonist 7 can be used for research of neurodegenerative diseases .

HY-10030

Mardepodect succinate PF-2545920 succinate	Phosphodiesterase (PDE)	Neurological Disease
Mardepodect succinate (PF-2545920 succinate) is a potent and specific phosphodiesterase 10A (PDE10A) inhibitor with potential activity in the treatment of schizophrenia. Mardepodect succinate has been further optimized to improve brain penetration and compound-like properties for use in schizophrenia research .

HY-131194

JAK2/STAT3-IN-1	Interleukin Related	Cancer
JAK2/STAT3-IN-1 (compound (S)-10a) is a potent GP130 inhibitor with an IC₅₀ of 3.04 µM. JAK2/STAT3-IN-1 shows anti-tumor activity .

HY-172407

KOR agonist 5	Opioid Receptor	Others
KOR agonist 5 (Compound 10a) is a KOR/MOR modulator with agonistic activity towards KOR and antagonistic activity towards MOR. KOR agonist 5 can effectively block morphine-induced antinociception and inhibition of intestinal motility. KOR agonist 5 can be used in the research of Substance Use Disorder (SUD) .

HY-161663

Phosphodiesterase-IN-2	Phosphodiesterase (PDE)	Cardiovascular Disease
Phosphodiesterase-IN-2 (Compound C7) is a selective, orally active inhibitor for phosphodiesterase 10A (PDE10A), with an IC₅₀ of 11.9 nM. Phosphodiesterase-IN-2 improves the stability of liver microsomes, and lowers BBB permeability. Phosphodiesterase-IN-2 exhibits good pharmacokinetic characters, and attenuates isoprenaline (HY-108353)-induced cardiac hypertrophic in mouse models .

HY-119467

MDK0734	Ser/Thr Protease	Cancer
MDK0734 is a selective inhibitor that inhibits feline hepsin B endopeptidase and exopeptidase activities. MDK0734 demonstrated efficacy in a cell-based in vitro tumor invasion model, significantly attenuating the invasive ability of MCF-10A neoT cells. MDK0734 provides new potential inhibitors for the development of clinically useful compounds targeting the deleterious effects of feline hepsin B in cancer progression .

HY-159515

PBE-AMF	Apoptosis DNA/RNA Synthesis Reactive Oxygen Species (ROS)	Cancer
PBE-AMF is a prodrug that activates H₂O₂ with anticancer activity. PBE-AMF impedes tumor proliferation by inhibiting DNA synthesis, reducing ATP levels, inducing apoptosis, and arresting the cell cycle. PBE-AMF potently and selectively inhibits the proliferation of MDA-MB-231 cells (IC₅₀=6.4 μM) while sparing non-cancerous MCF-10A cells .

HY-116264

CatB-IN-1	Ser/Thr Protease	Cancer
CatB-IN-1 is an enzyme inhibitor with significant inhibitory activity against tumor invasion. CatB-IN-1 may reduce the invasiveness of tumor cells by regulating intracellular protein metabolism. CatB-IN-1 demonstrates effective anti-invasive ability in cell models and can significantly reduce the invasive ability of MCF-10A neoT cells. The structure-activity relationship study of CatB-IN-1 shows that its design can target multiple functions of cat hepsin B .

Cat. No.	Product Name	Target	Research Area

HY-P3171

Acetyl-(Cys4,D-Phe7,Cys10)-a-MSH (4-13)	Biochemical Assay Reagents	Others
Acetyl-(Cys4,D-Phe7,Cys10)-a-MSH (4-13) is a melanotropin cyclic peptide. Acetyl-(Cys4,D-Phe7,Cys10)-a-MSH (4-13) ultraprolongs melanotropic activity in frog and lizard skin model with great agonisim. Acetyl-(Cys4,D-Phe7,Cys10)-a-MSH (4-13) exhibits a complete resistance to tryptic degradation .

Cat. No.	Product Name	Target	Research Area	Image

HY-P99265

Mapatumumab HGS-ETR1; Anti-Human TNFRSF10A Recombinant Antibody	Inhibitory Antibodies	Cancer
Mapatumumab (HGS-ETR1) is a fully human IgG1 agonistic monoclonal antibody that targets tumor necrosis factor-related apoptosis-inducing ligand receptor 1 (TRAIL-R1). Mapatumumab can be used for the research of cancer .

HY-P99619

Finotonlimab SCT-I10A	PD-1/PD-L1	Cancer
Finotonlimab (SCT-I10A) is a recombinant humanised IgG PD-1 antibody. Finotonlimab has the potential for solid tumors or lymphomas research .

HY-P991111

*Anti-Mouse TIGIT Antibody (10A7)*	Transmembrane Glycoprotein	Inflammation/Immunology
Anti-Mouse TIGIT Antibody (10A7) is a mouse IgG2 monoclonal antibody that targets TIGIT. Recommend Isotype Controls: Mouse IgG2a kappa, Isotype Control (HY-P99978).

HY-P99147

*Anti-Mouse TCR V gamma 2 Antibody (UC3-10A6)*	CD3	Infection Inflammation/Immunology
Anti-Mouse TCR V gamma 2 Antibody (UC3-10A6) is an Armenian Hamster-derived IgG antibody inhibitor, targeting to mouse TCR V gamma 2. Anti-Mouse TCR V gamma 2 Antibody (UC3-10A6) reacts with an epitope on the delta chain of the mouse Vγ2 TCR (V gamma 2 T cell receptor). Anti-Mouse TCR V gamma 2 Antibody (UC3-10A6) can deplete γδ T cell. Anti-Mouse TCR V gamma 2 Antibody (UC3-10A6) can be used for the researches of infection and immunology, such as herpes simplex virus-1 (HSV-1) infection .

HY-P991826

*Anti-Mouse CD80 Antibody (16-10A1)*	Transmembrane Glycoprotein	Inflammation/Immunology
Anti-Mouse CD80 Antibody (16-10A1) reacts with mouse CD80 that can block CD80 in vivo. Recommend Isotype Controls: Polyclonal Armenian hamster IgG, Isotype Control (HY-P990305) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N10922

*(3S,4aS,10aS)-3-(Acetyloxy)-2,3,4,4a,10,10a-hexahydro-6-hydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-9(1H)-phenanthrenone*	Terpenoids Celastraceae Diterpenoids Celastrus Plants Source Classification	Others
(3S,4aS,10aS)-3-(Acetyloxy)-2,3,4,4a,10,10a-hexahydro-6-hydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-9(1H)-phenanthrenone (compound 3), a Palmitate, can be isolated from the root tissue of Salvia miltiorrhiza. (3S,4aS,10aS)-3-(Acetyloxy)-2,3,4,4a,10,10a-hexahydro-6-hydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-9(1H)-phenanthrenone (compound 3) shows anti-cancer activity against human cancer cell lines with DC₅₀s of 25.5 μg/mL (HeLa), 37.5 μg/mL (HepG2), 30.2 μg/mL (OVCAR-3), respectively .

HY-N2704

*1H-2,10a-Ethanophenanthrene, kaur-16-en-18-oic acid deriv.*	Other Terpenoids Structural Classification Terpenoids Pteridaceae Plants Pteris livida Mett. Source Classification	Drug Derivative
1H-2,10a-Ethanophenanthrene, kaur-16-en-18-oic acid deriv. is a derivated compound isolated from the Pteridaceae plants of Costa Rica .

Species:	Virus (2) Human (13) Mouse (2) Cynomolgus (1) Canine (1)
Tag:	His (14) Tag Free (2) Avi (4) Fc (3)
Source:	HEK293 (16) Sf9 insect cells (1) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P72440

	TRAIL R1/TNFRSF10A Protein, Human (HEK293, His) Tumor necrosis factor receptor superfamily member 10A; TRAIL-R1; CD261; TNFRSF10A; APO2; DR4	Human	HEK293
	TRAIL R1/TNFRSF10A protein is a receptor for TNFSF10/TRAIL, which recruits caspase-8 through FADD to initiate cell apoptosis and form a death-inducing signaling complex (DISC). It activates NF-kappa-B and interacts with TRADD and RIPK1 in the monomeric state. TRAIL R1/TNFRSF10A Protein, Human (HEK293, His) is the recombinant human-derived TRAIL R1/TNFRSF10A protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P74500

	TRAIL R1/TNFRSF10A Protein, Human (HEK293, hFc) Tumor necrosis factor receptor superfamily member 10A; TRAIL-R1; CD261; APO2; DR4	Human	HEK293
	TRAIL R1/TNFRSF10A protein is a receptor for TNFSF10/TRAIL, which recruits caspase-8 through FADD to initiate cell apoptosis and form a death-inducing signaling complex (DISC). It activates NF-kappa-B and interacts with TRADD and RIPK1 in the monomeric state. TRAIL R1/TNFRSF10A Protein, Human (HEK293, hFc) is the recombinant human-derived TRAIL R1/TNFRSF10A protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P74501

	TRAIL R1/TNFRSF10A Protein, Human (131a.a, HEK293, His) Tumor necrosis factor receptor superfamily member 10A; TRAIL-R1; CD261; APO2; DR4	Human	HEK293
	TRAIL R1/TNFRSF10A protein is a receptor for TNFSF10/TRAIL, which recruits caspase-8 through FADD to initiate cell apoptosis and form a death-inducing signaling complex (DISC). It activates NF-kappa-B and interacts with TRADD and RIPK1 in the monomeric state. TRAIL R1/TNFRSF10A Protein, Human (239a.a, HEK293, His) is the recombinant human-derived TRAIL R1/TNFRSF10A, expressed by HEK293, with C-His labeled tag.

HY-P78529

	TRAIL R1/TNFRSF10A Protein, Human (HEK293, His-Avi) DR4; CD261; TNFRSF10A; TRAIL-R; APO2; TRAIL R1; MGC9365	Human	HEK293
	TRAIL R1/TNFRSF10A protein is a receptor for TNFSF10/TRAIL, which recruits caspase-8 through FADD to initiate cell apoptosis and form a death-inducing signaling complex (DISC). It activates NF-kappa-B and interacts with TRADD and RIPK1 in the monomeric state. TRAIL R1/TNFRSF10A Protein, Human (HEK293, His-Avi) is the recombinant human-derived TRAIL R1/TNFRSF10A protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P78219

	TRAIL R1/TNFRSF10A Protein, Human (Biotinylated, HEK293, His-Avi) DR4; CD261; TNFRSF10A; TRAIL-R; APO2; TRAIL R1; MGC9365	Human	HEK293
	TRAIL R1/TNFRSF10A protein is a receptor for TNFSF10/TRAIL, which recruits caspase-8 through FADD to initiate cell apoptosis and form a death-inducing signaling complex (DISC). It activates NF-kappa-B and interacts with TRADD and RIPK1 in the monomeric state. TRAIL R1/TNFRSF10A Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived TRAIL R1/TNFRSF10A protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P72689

	CLEC10A/CD301 Protein, Human (HEK293, His) C-type lectin domain family 10 member A; CD301; CLEC10A; CLECSF13; CLECSF14; HML	Human	HEK293
	CLEC10A/CD301 Protein, implicated in probable immune response regulation, binds Tn-Ag sugar moieties in a calcium-dependent manner. Recognizing these structures on carcinoma cells, CLEC10A/CD301 suggests a role in immune surveillance. Further exploration of its molecular interactions and downstream signaling pathways will enhance understanding of its contributions to immune modulation, especially in the context of cancer immunity. CLEC10A/CD301 Protein, Human (HEK293, His) is the recombinant human-derived CLEC10A/CD301 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P75676

	CLEC10A/CD301 Protein, Human (HEK293, Fc) C-type lectin domain family 10 member A; CD301; CLEC10A; CLECSF13; CLECSF14; HML	Human	HEK293
	CLEC10A/CD301 Protein, implicated in probable immune response regulation, binds Tn-Ag sugar moieties in a calcium-dependent manner. Recognizing these structures on carcinoma cells, CLEC10A/CD301 suggests a role in immune surveillance. Further exploration of its molecular interactions and downstream signaling pathways will enhance understanding of its contributions to immune modulation, especially in the context of cancer immunity. CLEC10A/CD301 Protein, Human (HEK293, Fc) is the recombinant human-derived CLEC10A/CD301 protein, expressed by HEK293 , with N-hFc labeled tag.

HY-P76265

	CLEC10A/CD301 Protein, Mouse (HEK293, Fc) C-type lectin domain family 10 member A; CD301; CLEC10A; CLECSF13; CLECSF14; HML	Mouse	HEK293
	CLEC10A/CD301 has predicted carbohydrate-binding activity and plays an upstream role in connective tissue replacement in inflammatory responses and wound healing. This protein is expected to be located on the membrane and be an integral part of the membrane structure, being active on the outside of the plasma membrane. CLEC10A/CD301 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CLEC10A/CD301 protein, expressed by HEK293 , with N-hFc labeled tag.

HY-P76266

	CLEC10A/CD301 Protein, Mouse (HEK293, His) C-type lectin domain family 10 member A; CD301; CLEC10A; CLECSF13; CLECSF14; HML	Mouse	HEK293
	The CLEC10A/CD301 protein is a receptor that recognizes terminal galactose and N-acetylgalactosamine units and is involved in a variety of biological processes.It may play a crucial role by promoting interactions between tumor-killing macrophages and tumor cells.CLEC10A/CD301 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CLEC10A/CD301 protein, expressed by HEK293 , with C-His labeled tag.

HY-P700740

	IL-10 Protein, Cynomolgus (HEK293, His) Interleukin-10; IL-10; CSIF; IL10A; TGIF; B-TCGF; GVHDS; MGC126450; MGC126451	Cynomolgus	HEK293
	IL-10 Protein, a key immune regulatory cytokine, centrally modulates immune responses. IL-10 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IL-10 protein, expressed by HEK293 , with N-His labeled tag.

HY-P78460

	IL-10 Protein, Human (HEK293, His-Avi) Interleukin-10; IL-10; CSIF; IL10A; TGIF; B-TCGF; GVHDS; MGC126450; MGC126451	Human	HEK293
	IL-10 protein is a major immunoregulatory cytokine with profound anti-inflammatory functions that limits excessive tissue destruction caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptors IL10RA and IL10RB, leading to JAK1- and STAT2-mediated phosphorylation of STAT3, which translocates to the nucleus and drives the expression of anti-inflammatory mediators. IL-10 Protein, Human (HEK293, His-Avi) is the recombinant human-derived IL-10 protein, expressed by HEK293 , with N-His, N-Avi labeled tag.

HY-P78144

	IL-10 Protein, Human (Biotinylated, HEK293, His-Avi) Interleukin-10; IL-10; CSIF; IL10A; TGIF; B-TCGF; GVHDS; MGC126450; MGC126451	Human	HEK293
	IL-10 protein is a major immunoregulatory cytokine with profound anti-inflammatory functions that limits excessive tissue destruction caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptors IL10RA and IL10RB, leading to JAK1- and STAT2-mediated phosphorylation of STAT3, which translocates to the nucleus and drives the expression of anti-inflammatory mediators. IL-10 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived IL-10 protein, expressed by HEK293 , with N-His, N-Avi labeled tag.

HY-P79268

	IL-10 Protein, Canine IL10; CSIF; CSIFMGC126450; Cytokine synthesis inhibitory factor; IL10A; IL-10MGC126451; interleukin-10; TGIF; Interleukin 10	Canine	E. coli
	IL-10 is the most important cytokine that inhibits pro-inflammatory responses and limits excessive immune responses in various autoimmune diseases. It belongs to the type 2 cytokine superfamily. IL-10 plays an important role in transmitting information, activating and regulating immune cells, mediating T and B cell activation, proliferation and differentiation, and in inflammatory responses. IL-10 can promote the proliferation and activation of CD8T⁺ cells, enhancing anti-tumor capabilities. IL-10 Protein, Canine is the recombinant canine-derived IL-10 protein, expressed by E. coli , with tag free.

HY-P700073AF

	Animal-Free Galectin-10 Protein, Human (His) GAL10; Gal-10; LGALS10; LGALS10A; LPPL_HUMAN; Charcot-Leyden crystal protein (CLC); Eosinophil lysophospholipase; Lysolecithin acylhydrolase	Human	E. coli
	Galectin-10 Protein, pivotal in immune regulation, recognizes cell-surface glycans, inducing anergy and suppressing CD25-positive regulatory T-cells (Treg). Interacting with CEL, it modulates immune responses, highlighting its significance in orchestrating immunoregulatory cellular processes. Animal-Free Galectin-10 Protein, Human (His) is the recombinant human-derived animal-FreeGalectin-10 protein, expressed by E. coli , with N-His labeled tag. This product is for cell culture use only.

HY-P77024

	HA1/Hemagglutinin Protein, H17N10 (AFC35418, HEK293, His) Influenza A H17N10 (A/little yellow-shouldered bat/Guatemala/164/2009) Hemagglutinin Protein (His)	Virus	HEK293
	The hemagglutinin (HA) protein is essential for viral attachment to host cells, binding to sialic acid receptors, and initiating virion internalization through clathrin-dependent or -independent pathways. As a class I viral fusion protein, HA determines host range and virulence, mediating viral penetration into the cytoplasm. Hemagglutinin/HA Protein, H17N10 (AFC35418, HEK293, His) is the recombinant Virus-derived Hemagglutinin/HA protein, expressed by HEK293 , with C-His labeled tag.

HY-P70751

	IL-10 Protein, Human (HEK293) 1 Publications Verification Interleukin-10; IL-10; Cytokine synthesis inhibitory factor; CSIF; IL10; RP11-262N9.1; IL10A; MGC126450; MGC126451; TGIF	Human	HEK293
	IL-10 protein is a major immunoregulatory cytokine with profound anti-inflammatory functions that limits excessive tissue destruction caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptors IL10RA and IL10RB, leading to JAK1- and STAT2-mediated phosphorylation of STAT3, which translocates to the nucleus and drives the expression of anti-inflammatory mediators. IL-10 Protein, Human (HEK293) is the recombinant human-derived IL-10 protein, expressed by HEK293 , with tag free.

HY-P77023

	HA/Hemagglutinin Protein, H17N10 (AFC35418, sf9, His) Influenza A H17N10 (A/little yellow-shouldered bat/Guatemala/164/2009) Hemagglutinin / HA Protein (His)	Virus	Sf9 insect cells
	The hemagglutinin (HA) protein is essential for viral attachment to host cells, binding to sialic acid receptors, and initiating virion internalization through clathrin-dependent or -independent pathways. As a class I viral fusion protein, HA determines host range and virulence, mediating viral penetration into the cytoplasm. Hemagglutinin/HA Protein, H17N10 (AFC35418, sf9, His) is the recombinant Virus-derived Hemagglutinin/HA protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P705614

	SLC10A2 Protein-VLP, Human (HEK293, His) Apical sodium-dependent bile acid transporter; ASBT; Ileal sodium-dependent bile acid transporter; IBAT; ISBT; Na+; Sodium/taurocholate cotransporting polypeptide, ileal; Solute carrier family 10 member 2	Human	HEK293
	SLC10A2 Protein-VLP, Human (HEK293, His) is recommended for animal immunization, ELISA. It is not recommended for receptor-ligand interaction detection and SPR/BLI assay since there are other irrelevant membrane proteins of the host on the VLP envelope, and the receptor-ligand interaction will have strong background interference. High requirements for chips and experimental protocols are needed for SPR/BLI assays. If VLP control is required, it is recommended HY-P701236. Tags can only be detected under denaturing conditions.

HY-P702498

	ADAM10 Protein, Human (HEK293, His) a disintegrin and metalloprotease domain 10; a disintegrin and metalloproteinase domain 10; AD10; ADAM 10; ADAM metallopeptidase domain 10; ADAM10; CD156c antigen; CD156c; CDw156; disintegrin and metalloproteinase domain-containing protein 10; EC 3.4.24; HsT18717; kuz; Kuzbanian protein homolog; Kuzbanian; MADM; MADMEC 3.4.24.81; Mammalian disintegrin-metalloprotease	Human	HEK293
	The ADAM10 protein cleaves TNF-α precursor, releasing a soluble form, and mediates the proteolytic release of JAM3 and various cell surface proteins. ADAM10 Protein, Human (HEK293, His) is the recombinant human-derived ADAM10 protein, expressed by HEK293 , with C-10*His labeled tag.

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Products	In-stock - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name	Chemical Structure

HY-166876S

Nicergoline impurity 18-d4
Nicergoline impurity 18-d₄ is deuterium labeled ((6aR,9R,10aS)-10a-Methoxy-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methanol (Nicergoline Impurity) .

HY-W654262

10α-Methoxy-9,10-dihydrolysergol-d3
10α-Methoxy-9,10-dihydrolysergol-d₃ is deuterium labeled ((6aR,9R,10aS)-10a-Methoxy-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methanol (Nicergoline Impurity) .

HY-W743954

Nicergoline impurity 11-d3
Nicergoline impurity 11-d₃ is deuterium labeled ((6aR,9R,10aS)-10a-Methoxy-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methanol (Nicergoline Impurity) .

Host:	Mouse (7) Rat (1) Rabbit (16)
Reactivity:	Human (23) mouse (1) Bovine (1) Rat (7) Mouse (9) Goat (1) Dog (1) Pig (1)
Application:	IHC-P (11) ICC/IF (12) mIHC (1) IF-Tissue (4) IP (3) IHC-F (1) WB (20) FC (11) ELISA (3)
Isotype:	IgG (16) IgG1 (4) IgG2a (1)
Conjugation:	Non-conjugated (24) Biotin (2)
Clonality:	Polyclonal (1) Monoclonal (16) Recombinant (13)
Modification:	Unmodified (19)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P87358

	PDE10A Antibody (YA7041) 5''-cyclic phosphodiesterase 10A antibody; cAMP and cAMP inhibited cGMP 3'5' cyclic phosphodiesterase 10A antibody; cAMP and cAMP-inhibited cGMP 3'' antibody; FLJ11894 antibody; HSPDE 10A antibody; HSPDE10A antibody; PDE 10A antibody; PDE10_HUMAN antibody; Pde10A antibody; Phosphodiesterase 10A antibody	WB, IHC-P, FC	Human, Mouse, Rat
	PDE10A Antibody (YA7041) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PDE10A.

HY-P81237

	Wnt10a Antibody FLJ14301; OODD; Protein Wnt-10A ; SSPS; STHAG4; Wingless type MMTV integration site family member 10A antibody; WN10A_HUMAN; wnt10A;	WB, ELISA	Human, Mouse, Goat
	Wnt10a Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Wnt10a.

HY-P87611

	RPL10A Antibody (YA7295)	WB, IHC-P, IHC-F, IF-Tissue, FC, ICC/IF	Human
	RPL10A Antibody (YA7295) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RPL10A.

HY-P810180

	*CLEC-10A* Antibody (YA9524)**	WB, ICC/IF, IF-Tissue, FC, IP	mouse
	CLEC-10A Antibody (YA9524) is a Rat-derived and non-conjugated IgG2a monoclonal antibody, targeting to CLEC-10A.

HY-P82135

	RPL10A Antibody (YA1880) RPL10A; NEDD6; 60S ribosomal protein L10A; CSA-19; Neural precursor cell expressed developmentally down-regulated protein 6; NEDD-6	WB	Human, Mouse, Rat
	RPL10A Antibody (YA1880) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RPL10A.

HY-P87404

	DR4/TNFRSF10A Antibody (YA7092)	WB, ICC/IF, FC	Human
	DR4/TNFRSF10A Antibody (YA7092) is a Rabbit-derived and non-conjugated IgG recombinant monoclonal antibody, targeting to DR4/TNFRSF10A.

HY-P87428

	CLEC10A/CD301 Antibody (YA7116)	FC, ELISA	Human
	CLEC10A/CD301 Antibody (YA7116) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CLEC10A/CD301.

HY-P89079

	TCP10 Antibody (YA8763) TCP10A	IHC-P	Human
	TCP10 Antibody (YA8763) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TCP10.

HY-P82135A

	RPL10A Antibody (YA1880)(PBS only) RPL10A; NEDD6; 60S ribosomal protein L10A; CSA-19; Neural precursor cell expressed developmentally down-regulated protein 6; NEDD-6	WB	Human, Mouse, Rat
	RPL10A Antibody (YA1880) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RPL10A.

HY-P87404A

	DR4/TNFRSF10A Antibody (YA7092)(PBS only)	WB, ICC/IF, FC	Human
	DR4/TNFRSF10A Antibody (YA7092) is a Rabbit-derived and non-conjugated IgG Recombinant monoclonal antibody, targeting to DR4/TNFRSF10A.

HY-P87428A

	CLEC10A/CD301 Antibody (YA7116)(PBS only)	FC, ELISA	Human
	CLEC10A/CD301 Antibody (YA7116) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CLEC10A/CD301.

HY-P89079A

	TCP10 Antibody (YA8763)(PBS only) TCP10A	IHC-P	Human
	TCP10 Antibody (YA8763) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TCP10.

HY-P81993

	Hsc70 Interacting Protein Antibody (YA1738) HIP; HOP; P48; AAG2; SNC6; HSPABP; FAM10A1; FAM10A4; HSPABP1; ST13	WB, IHC-P, ICC/IF, FC	Human, Mouse
	Hsc70 Interacting Protein Antibody (YA1738) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Hsc70 Interacting Protein.

HY-P82437

	RHOQ Antibody (YA2182) ARHQ; RASL7A; Rho related GTP binding protein RhoQ; Rhoq; TC10A	WB, ICC/IF	Human, Rat
	RHOQ Antibody (YA2182) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RHOQ.

HY-P85433

	Hsc70 Interacting Protein Antibody (YA5125) ST13; AAG2; FAM10A1; HIP; SNC6; Hsc70-interacting protein; Hip; Aging-associated protein 2; Progesterone receptor-associated p48 protein; Protein FAM10A1; Putative tumor suppressor ST13; Renal carcinoma antigen NY-REN-33; Suppression of tum	WB, IHC-P, ICC/IF	Human, Bovine, Dog, Pig
	Hsc70 Interacting Protein Antibody (YA5125) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Hsc70 Interacting Protein.

HY-P81102

	Collagen X Antibody (YA3502) 1 Publications Verification COAA1_HUMAN antibody; Col10A 1 antibody; COL10A1 antibody; Collagen alpha 1(X) chain antibody; Collagen alpha-1(X) chain antibody; Collagen type X alpha 1 (Schmid metaphyseal chondrodysplasia) antibody; Collagen type X alpha 1 antibody; Collagen X alpha 1 polypeptide antibody; CollagenX antibody; fa66d11 antibody; fb10c08 antibody; OTTHUMP00000040411 antibody; Procollagen type X alpha 1 antibody; Schmid metaphyseal chondrodysplasia antibody; wu:fa66d11 antibody; wu:fb10c08 antibody;	WB	Human, Mouse, Rat
	Collagen X Antibody (YA3502) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Collagen X.

HY-P82241

	TNPO3 Antibody (YA1986) TNPO 3; Imp12; Importin 12; IPO12; MTR10A; TNPO3; Transportin 3; Transportin SR; TRN-SR2; TRNSR	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	TNPO3 Antibody (YA1986) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TNPO3.

HY-P81113

	IL-10 Antibody (YA3521) Interleukin-10 precursor; Cytokine synthesis inhibitory factor; CSIF; Cytokine Synthesis Inhibitory Factor; IL 10; IL10A; Interleukin 10; Interleukin10; MGC126450; MGC126451; TGIF; IL10_HUMAN. 白介素10	WB, ICC/IF, FC	Human
	IL-10 Antibody (YA3521) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IL-10.

HY-P84952

	IL-10 Antibody (YA4644) Interleukin-10 precursor; Cytokine synthesis inhibitory factor; CSIF; Cytokine Synthesis Inhibitory Factor; IL 10; IL10A; Interleukin 10; Interleukin10; MGC126450; MGC126451; TGIF; IL10_HUMAN. 白介素10	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	IL-10 Antibody (YA4644) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IL-10.

HY-P81425

	S100 A8 Antibody (YA1170) Calgranulin-A antibody; Calprotectin L1L subunit antibody; CFAG antibody; Cystic fibrosis antigen antibody; Leukocyte L1 complex light chain antibody; Migration inhibitory factor-related protein 8 antibody; MRP-8 antibody; N-terminally processed antibody; p8 antibody; Protein S100-A8 antibody; S100 calcium-binding protein A8 antibody; S100A8 antibody; S10A8_HUMAN antibody; Urinary stone protein band A antibody	WB, IHC-P, ICC/IF, IP, FC, IF-Tissue	Human
	S100 A8 Antibody (YA1170) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to S100 A8.

HY-P85626

	S100A4 Antibody (YA5318) 18A2; 42A; calcium Placental protein; Calvasculin; CAPL; Fibroblast specific protein 1; Fibroblast specific protein; FSP1; Leukemia multidrug resistance associated protein; Malignant transformation suppression 1; Metastasin; MTS1; OTTHUMP00000015467; OTTHUMP00000015468; P9KA; PEL98; Placental calcium-binding protein; Protein Mts1; Protein S100 A4; Protein S100-A4; S100 calcium binding protein A4; calcium protein, calvasculin, metastasin, murine placental homolog; S100 calcium binding protein A4; S100 calcium-binding protein A4; S100a4; S10A4_HUMAN.	WB	Human
	S100A4 Antibody (YA5318) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to S100A4.

HY-P85626A

	S100A4 Antibody (YA5318)(PBS only) 18A2; 42A; calcium Placental protein; Calvasculin; CAPL; Fibroblast specific protein 1; Fibroblast specific protein; FSP1; Leukemia multidrug resistance associated protein; Malignant transformation suppression 1; Metastasin; MTS1; OTTHUMP00000015467; OTTHUMP00000015468; P9KA; PEL98; Placental calcium-binding protein; Protein Mts1; Protein S100 A4; Protein S100-A4; S100 calcium binding protein A4; calcium protein, calvasculin, metastasin, murine placental homolog; S100 calcium binding protein A4; S100 calcium-binding protein A4; S100a4; S10A4_HUMAN.	WB	Human
	S100A4 Antibody (YA5318) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to S100A4.

HY-P80317

	S100A4 Antibody (YA084) 18A2 antibody; 42A antibody; calcium Placental protein antibody; Calvasculin antibody; CAPL antibody; Fibroblast specific protein 1 (FSP1) antibody; Fibroblast specific protein 1 antibody; Fibroblast specific protein antibody; FSP1 antibody; Leukemia multidrug resistance associated protein antibody; Malignant transformation suppression 1 (MTS1) antibody; Malignant transformation suppression 1 antibody; Metastasin antibody; MTS1 antibody; OTTHUMP00000015467 antibody; OTTHUMP00000015468 antibody; P9KA antibody; PEL98 antibody; Placental calcium-binding protein antibody; Protein Mts1 antibody; Protein S100 A4 antibody; Protein S100-A4 antibody; S100 calcium binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog) antibody; S100 calcium binding protein A4 antibody; S100 calcium-binding protein A4 antibody; S100a4 antibody; S10A4_HUMAN antibody;	WB, ICC/IF, IHC-P, IP, FC	Human, Mouse
	S100A4 Antibody (YA084) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to S100A4.

HY-P83734

	S100A9 Antibody(YA3464) Leukocyte L1 complex heavy chain antibody; 60B8AG antibody; CAGB antibody; Calgranulin B antibody; Calgranulin-B antibody; Calprotectin L1H subunit antibody; CFAG antibody; CGLB antibody; Cystic fibrosis antigen B antibody; L1AG antibody; Leukocyte L1 complex heavy chain antibody; LIAG antibody; MAC387 antibody; MIF antibody; Migration inhibitory factor related protein 14 antibody; Migration inhibitory factor-related protein 14 antibody; MRP 14 antibody; MRP-14 antibody; MRP14 antibody; Myeloid-related protein 14 antibody; NIF antibody; OTTHUMP00000015331 antibody; p14 antibody; Protein S100-A9 antibody; S100 A9 antibody; S100 calcium binding protein A9 antibody; S100 calcium binding protein A9 calgranulin B antibody; S100 calcium-binding protein A9 antibody; S100A9 antibody; S10A9_HUMAN antibody;	WB, IHC-P, IF-Tissue, mIHC	Human
	S100A9 Antibody(YA3464) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to S100A9.

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Products	In-stock - + Add to Cart
Cat. No.
Host
Reactivity
Application
Dilution Ratio
Molecular Weight
Conjugation
Clonality
Immunogen
Appearance
Isotype
Gene ID
SwissProt ID
Purity
Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-R00059

*hsa-miR-10a-5p mimic*		MicroRNAs miRNA mimics
hsa-miR-10a-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-RI00059

*hsa-miR-10a-5p inhibitor*		MicroRNAs miRNA inhibitors
hsa-miR-10a-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RS18435

Clec10a Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Clec10a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Clec10a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS15828

WNT10A Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
WNT10A Human Pre-designed siRNA Set A contains three designed siRNAs for WNT10A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-R00058

*hsa-miR-10a-3p mimic*		MicroRNAs miRNA mimics
hsa-miR-10a-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-174499

Cas9 Nickase D10A mRNA (5moU)		mRNA Gene Editing
Cas9 Nickase D10A mRNA expresses a version of the Streptococcus pyogenes SF370 Cas9 protein (CRISPR Associated Protein 9) that contains a D10A amino acid substitution. This mRNA also contains a C-terminal nuclear localization signal followed by a HA tag.Cas9 functions as part of the CRISPR (clustered regularly interspaced short palindromic repeats) genome editing system. In the CRISPR system, an RNA guide sequence targets the site of interest and the Cas9 protein is employed to perform the DNA cleavage. While wild-type Cas9 creates a double-stranded break at the target site, Cas9 nickase creates a single-stranded break. This favors homology-directed repair and decreases the occurrence of non-homologous end joining.

HY-RI00058A

*hsa-miR-10a-3p antagomir*		MicroRNAs miRNA antagomirs
hsa-miR-10a-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI00058

*hsa-miR-10a-3p inhibitor*		MicroRNAs miRNA inhibitors
hsa-miR-10a-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RS10201

Pde10a Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Pde10a Rat Pre-designed siRNA Set A contains three designed siRNAs for Pde10a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS03036

COQ10A Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
COQ10A Human Pre-designed siRNA Set A contains three designed siRNAs for COQ10A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS10199

PDE10A Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
PDE10A Human Pre-designed siRNA Set A contains three designed siRNAs for PDE10A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS15087

TRMT10A Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
TRMT10A Human Pre-designed siRNA Set A contains three designed siRNAs for TRMT10A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS24917

Clec10a Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Clec10a Rat Pre-designed siRNA Set A contains three designed siRNAs for Clec10a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS10200

Pde10a Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Pde10a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pde10a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS14795

TNFRSF10A Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
TNFRSF10A Human Pre-designed siRNA Set A contains three designed siRNAs for TNFRSF10A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS01171

ATP10A Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ATP10A Human Pre-designed siRNA Set A contains three designed siRNAs for ATP10A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS12520

Scn10a Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Scn10a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Scn10a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS12521

Scn10a Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Scn10a Rat Pre-designed siRNA Set A contains three designed siRNAs for Scn10a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS12519

SCN10A Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
SCN10A Human Pre-designed siRNA Set A contains three designed siRNAs for SCN10A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS12161

RPL10A Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
RPL10A Human Pre-designed siRNA Set A contains three designed siRNAs for RPL10A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS02779

CLEC10A Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
CLEC10A Human Pre-designed siRNA Set A contains three designed siRNAs for CLEC10A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS12993

SLC10A7 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
SLC10A7 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC10A7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS12989

SLC10A3 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
SLC10A3 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC10A3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS12986

SLC10A2 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
SLC10A2 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC10A2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS22028

Slc10a1 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Slc10a1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Slc10a1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS12992

SLC10A6 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
SLC10A6 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC10A6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS28546

Slc10a1 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Slc10a1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Slc10a1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS12987

Slc10a2 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Slc10a2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Slc10a2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS12990

SLC10A4 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
SLC10A4 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC10A4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS12988

Slc10a2 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Slc10a2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Slc10a2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS12991

SLC10A5 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
SLC10A5 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC10A5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-R00059A

*hsa-miR-10a-5p agomir*		MicroRNAs miRNA agomirs
hsa-miR-10a-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R00058A

*hsa-miR-10a-3p agomir*		MicroRNAs miRNA agomirs
hsa-miR-10a-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI00059A

*hsa-miR-10a-5p antagomir*		MicroRNAs miRNA antagomirs
hsa-miR-10a-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RS27752

Col10a1 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Col10a1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Col10a1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS12985

SLC10A1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
SLC10A1 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC10A1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS02959

COL10A1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
COL10A1 Human Pre-designed siRNA Set A contains three designed siRNAs for COL10A1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS21235

Col10a1 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Col10a1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Col10a1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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