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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
180 Results for "
10A
" in MedChemExpress (MCE) Product Catalog:
Products (180)
180 Results for "10A" in MCE Product Catalog:
7
7 Publications Verification
Cat. No.: HY-P70517
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL10; TGIF; Interleukin 10; T-Cell Growth Inhibitory Factor; IL-10; Interleukin-10; CSIF; Interleukin Family Protein; Cytokine Synthesis Inhibitory Factor; GVHDS; IL10A; IF2A
4
4 Cited Publications
Cat. No.: HY-P7030
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL10; TGIF; Interleukin 10; T-Cell Growth Inhibitory Factor; IL-10; Interleukin-10; CSIF; Interleukin Family Protein; Cytokine Synthesis Inhibitory Factor; GVHDS; IL10A; IF2A
4
4 Cited Publications
Cat. No.: HY-P7030A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL10; TGIF; Interleukin 10; T-Cell Growth Inhibitory Factor; IL-10; Interleukin-10; CSIF; Interleukin Family Protein; Cytokine Synthesis Inhibitory Factor; GVHDS; IL10A; IF2A
2
2 Cited Publications
Cat. No.: HY-P7098A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL10; TGIF; Interleukin 10; T-Cell Growth Inhibitory Factor; IL-10; Interleukin-10; CSIF; Interleukin Family Protein; Cytokine Synthesis Inhibitory Factor; GVHDS; IL10A; IF2A
1
1 Cited Publications
Target:
Research Areas:
THPP-1, a SGC chemical probe, is a potent and orally bioavailable phosphodiesterase 10A (PDE10A) inhibitor, with Ki values of 1 nM and 1.3 nM for human and rat PDE10A, respectively. THPP-1 has excellent pharmacokinetic properties in preclinical species .
1
1 Cited Publications
Cat. No.: HY-P81102
Synonyms: COAA1_HUMAN antibody;
Col10A 1 antibody;
COL10A1 antibody;
Collagen alpha 1(X) chain antibody;
Collagen alpha-1(X) chain antibody;
Collagen type X alpha 1 (Schmid metaphyseal chondrodysplasia) antibody;
Collagen type X alpha 1 antibody;
Collagen X alpha 1 polypeptide antibody;
CollagenX antibody;
fa66d11 antibody;
fb10c08 antibody;
OTTHUMP00000040411 antibody;
Procollagen type X alpha 1 antibody;
Schmid metaphyseal chondrodysplasia antibody;
wu:fa66d11 antibody;
wu:fb10c08 antibody;
1
1 Cited Publications
Cat. No.: HY-P73154
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL10; TGIF; Interleukin 10; T-Cell Growth Inhibitory Factor; IL-10; Interleukin-10; CSIF; Interleukin Family Protein; Cytokine Synthesis Inhibitory Factor; GVHDS; IL10A; IF2A
1
1 Cited Publications
Cat. No.: HY-P70751
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL10; TGIF; Interleukin 10; T-Cell Growth Inhibitory Factor; IL-10; Interleukin-10; CSIF; Interleukin Family Protein; Cytokine Synthesis Inhibitory Factor; GVHDS; IL10A; IF2A
1
1 Cited Publications
Cat. No.: HY-P73153
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: IL10; TGIF; Interleukin 10; T-Cell Growth Inhibitory Factor; IL-10; Interleukin-10; CSIF; Interleukin Family Protein; Cytokine Synthesis Inhibitory Factor; GVHDS; IL10A; IF2A
1
1 Cited Publications
Cat. No.: HY-P71082
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: S100A6; Protein S100-A6; Prev. CACY; S100 Calcium-Binding Protein A6 (Calcyclin); PRA; S100 Calcium-Binding Protein A6; Calcyclin; S100 Calcium-Binding Protein; CABP; Protein S100; 2A9; S10A6; Prolactin Receptor-Associated Protein; 5B10; Growth Factor-Ind
Cat. No.: HY-W116007
CAS No.: 556-67-2
Research Areas:
Octamethylcyclotetrasiloxane promotes the anchorage-independent growth of MCF-10A and MCF-10F cells. Octamethylcyclotetrasiloxane induces DNA damage, inhibits the expression of DNA-repairing protein BRCA1 under long-term and high-concentration exposure. Octamethylcyclotetrasiloxane exhibits intrinsic estrogenic activity .
Cat. No.: HY-144666
Purity: 99.64%
Target:
Research Areas:
GLS-1-IN-1 (compound 1d) is a GLS-1 inhibitor. GLS-1-IN-1 shows inhibitory effect against Hep G2, MCF 7, and MCF 10A cells .
Target:
Research Areas:
M4 mAChR agonist-1 (compound 10a) is a potent M4 mAChR agonist with an EC50 >10 μM for human M4 .
Cat. No.: HY-176976
CAS No.: 3076725-05-5
Target:
Research Areas:
Exatecan-mpGNNG (Compound 10a) is the linker-payload component of an antibody-drug conjugate (ADC). Exatecan-mpGNNG is composed of Exatecan (HY-13631), a potent topoisomerase I inhibitor, and the linker .
Cat. No.: HY-127024A
CAS No.: 1073179-55-1
Target:
Research Areas:
TR antagonist 2 (Compound 10a) is a competitive thyroid hormone receptors (TRα/β) antagonist (IC50=47 nM). TR antagonist 2 competes with triiodothyronine (T3) for binding to the ligand-binding domain of TR to block receptor-coactivator complex formation and inhibit target gene transcription, reducing thyroid hormone-mediated hypermetabolic effects. TR antagonist 2 is promising for research of hyperthyroidism (e.g., Graves' disease) and thyrotoxicosis .
Target:
Research Areas:
N-Methylbenzamide is a potent phosphodiesterase 10A (PDE10A) inhibitor. N-Methylbenzamide has anti-cancer activity .
Cat. No.: HY-18078
CAS No.: 927691-21-2
Target:
Research Areas:
PQ-10 is a potent inhibitor of Phosphodiesterase 10A (PDE10A) with IC50 andED50 of 4.6 nM and 13 mg/kg, respectively. PQ-10 induces patterns of brain glucose metabolism which can be a potential translational biomarker. PQ-10 has the potential for researching psychiatric disorders like schizophrenia .
Cat. No.: HY-151959
CAS No.: 3025841-47-5
Target:
Research Areas:
Cardiovascular Disease Metabolic Disease Inflammation/Immunology
FXR agonist 4 (compound 10a) is an agonist of farnesoid X receptor (FXR) with an EC50 value of 1.05 μM. FXR agonist 4 effectively improves hyperlipidemia, hepatic steatosis, insulin resistance and hepatic inflammation in DIO mice. FXR agonist 4 can be used for the research of non-alcoholic fatty liver disease (NAFLD) .
Cat. No.: HY-RI00059
hsa-miR-10a-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
