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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
293 T-Rex cells
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "293 T-Rex cells" in MCE Product Catalog:
6
6 Cited Publications
Cat. No.: HY-19976
CAS No.: 1024448-59-6
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RN-1747 is a selective TRPV4 channel agonist, with EC50 values of 0.77 μM, 4.0 μM and 4.1 μM for hTRPV4, mTRPV4 and rTRPV4, respectively. RN-1747 acts as an antagonist of TRPM8, with an IC50 of 4 μM. Topical cutaneous administration of RN-1747 induces hypothermia, increases tail heat loss via cutaneous vasodilation, and promotes cold-seeking behavior in rats. Intracerebroventricular administration of RN-1747 does not induce hypothermia in rats .
Cat. No.: HY-184953
CAS No.: 3099598-25-8
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Anticancer agent 345 is a heterobifunctional anticancer compound that exhibits weak antiproliferative activity against both ERα-overexpressing and non-overexpressing T-Rex 293 cells . Anticancer agent 345 can be used in cancer-related research .
Cat. No.: HY-147881
CAS No.: 2481321-20-2
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Anti-Influenza agent 3 (compound 11h) is a potent anti-influenza agent with EC50 values of 3.29, 2.45 µM for A/HK/68 (H3N2, M2-WT), A/WSN/33 (H1N1, M2-S31N) strain, respectively. Anti-Influenza agent 3 shows low cytotoxicity for MDCK epithelial cells. Anti-Influenza agent 3 inhibits the M2 WT and S31N ion channel conductivity .
Cat. No.: HY-184960
CAS No.: 3099599-58-0
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Anticancer agent 352 is a heterobifunctional anticancer compound. Anticancer agent 352 exhibits only weak antiproliferative activity against both ERα-overexpressing and non-overexpressing T-Rex 293 cells induced by Doxorubicin (HY-15142A). Anticancer agent 352 can be used in breast cancer-related research .
Cat. No.: HY-184900
CAS No.: 3099598-43-0
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Anticancer agent 341 (Compound III-163) is a non-ERα-dependent cytotoxic agent with its GI50 for MCF cells is 0.05-0.5 μΜ. Anticancer agent 341 exhibits GI50 for T-Rex 293 cells regardless of whether Doxycycline (Dox) (HY-N0565) is added of all < 0.05 μΜ. Anticancer agent 341 can be used in breast cancer research .
Cat. No.: HY-184948
CAS No.: 3099595-91-9
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Anticancer agent 347 is a heterobifunctional anticancer inhibitor with inhibitory activity against ERα-overexpressing cells and breast cancer cells. Anticancer agent 347 can be used for the research of breast cancer .
Cat. No.: HY-184952
CAS No.: 3099595-74-8
Anticancer agent 343 is a heterobifunctional anticancer compound and growth inhibitor with moderate cancer cell growth inhibitory activity. Anticancer agent 343 can be used for cancer research .
Cat. No.: HY-182723
CAS No.: 2094630-35-8
PSB-16671 is an allosteric agonist of GPR84. PSB-16671 recruits β-arrestins and couples to Gi, enhances the Gi activation potency of orthosteric agonists, and exerts a synergistic effect with orthosteric agonists. PSB-16671 promotes G protein activation and partial chemotaxis independent of GPR84 in mouse neutrophils, maintains the phagocytic function of macrophages against cancer cells without inducing receptor desensitization. PSB-16671 can be used in cancer-related research .
Cat. No.: HY-N20747
CAS No.: 28363-70-4
Synonyms: 4-Hydroxy-N-methyltryptamine; 4-HO-NMT
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
