Anticancer agent 347
Anticancer agent 347 is a heterobifunctional anticancer inhibitor with inhibitory activity against ERα-overexpressing cells and breast cancer cells. Anticancer agent 347 can be used for the research of breast cancer.
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- CAS No.: 3099595-91-9
- Formule: C46H53F3N10O3S
- Masse moléculaire:883.04
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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ERα |
Anticancer agent 347 (I-33) exhibits potent antiproliferative activity against MCF7 breast cancer cells (GI50 < 0.05 μM)[1].
Anticancer agent 347 exerts potent and selective antiproliferative effects on Doxorubicin (HY-15142A)-induced estrogen receptor α-overexpressing T-Rex 293 cells (GI50 < 0.05 μM), while shows extremely weak inhibitory activity against T-Rex 293 cells without high estrogen receptor α expression (GI50 > 2.5 μM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3099595-91-9
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Masse moléculaire 883.04
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Formule C46H53F3N10O3S
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SMILES
FC(F)(F)CN1[C@H](C2=CC=C(C=N2)NC3CN(C3)CCCOCCOCCOC4=CC=C(C5=N[C@@H](C)C6=NN=C(C)N6C7=C5C(C)=C(C)S7)C=C4)C8=C(C[C@H]1C)C9=CNN=C9C=C8
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anticancer agent 347 Related Classifications
HY-184948 Related Classifications
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