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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
37 Results for "
5-hydroxytryptamine (D)
" in MedChemExpress (MCE) Product Catalog:
Products (37)
37 Results for "5-hydroxytryptamine (D)" in MCE Product Catalog:
16
Target:
Research Areas:
Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
14
14 Cited Publications
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WAY-100635 is a potent and selective 5-HT1A Receptor antagonist with a pIC50 of 8.87, an apparent pA2 of 9.71.
WAY-100635 is a potent and selective 5-hydroxytryptamine 1A (5-HT1A) receptor antagonist with an IC50 value of 0.91 nM and Ki value of 0.39 nM. WAY-100635 has pIC50 values for 5-HT1A and α1-adrenergic receptors of 8.9 and 6.6, respectively. WAY-100635 is also a potent dopamine D4 receptor agonist .
14
14 Cited Publications
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WAY-100635 maleate is a potent and selective 5-hydroxytryptamine 1A (5-HT1A) receptor antagonist with an IC50 value of 0.91 nM and Ki value of 0.39 nM. WAY-100635 maleate has pIC50 values for 5-HT1A and α1-adrenergic receptors of 8.9 and 6.6, respectively. WAY-100635 maleate is also a potent dopamine D4 receptor agonist .
1
1 Cited Publications
Cat. No.: HY-B1473AS
CAS No.: 58264-95-2
Synonyms: 5-hydroxytryptamine-d4; 5-HT-d4
1
1 Cited Publications
Cat. No.: HY-A0019A
CAS No.: 199739-10-1
Synonyms: 9-Hydroxyrisperidone palmitate
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Research Areas:
Paliperidone palmitate is an orally effective competitive antagonist of dopamine D2 receptors and 5-hydroxytryptamine 2A (5-HT2A) receptors that can cross the blood-brain barrier. Paliperidone palmitate competitively inhibits the effects of dopamine and 5-hydroxytryptamine by binding to dopamine D2 receptors and 5-HT2A receptors, regulating the balance of the neurotransmitter system and thus exerting antipsychotic activity. Paliperidone palmitate is mainly used in the research field of schizophrenia .
1
1 Cited Publications
Category:
Natural Products Animals Marine natural products Other marine organisms Disease Research Fields Cancer
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1
1 Cited Publications
Cat. No.: HY-B1473S
CAS No.: 2469263-61-2
Synonyms: 5-hydroxytryptamine-d4 hydrochloride; 5-HT-d4 hydrochloride
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Synonyms: N-Acetylserotonin-d3; Normelatonin-d3; O-Demethylmelatonin-d3
Cat. No.: HY-P10447
CAS No.: 103651-09-8
Synonyms: Fengycin IX; SNA-60-367-3
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Cat. No.: HY-B0527AS
CAS No.: 203645-63-0
Cat. No.: HY-W010973S
CAS No.: 2687960-56-9
Cat. No.: HY-P4755
CAS No.: 282726-24-3
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Cat. No.: HY-B1473S2
CAS No.: 1269486-67-0
Synonyms: 5-hydroxytryptamine-13C,D4; 5-HT-13C,D4
Cat. No.: HY-15414S
CAS No.: 2140316-62-5
Synonyms: Lu AA 21004 d8
Cat. No.: HY-156807
CAS No.: 210751-39-6
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LY 367265 is a 5-hydroxytryptamine transporter (SERT) inhibitor (IC₅₀ = 3.1 nM) and a 5-HT₂A receptor antagonist (Kᵢ = 0.81 nM). LY 367265 has the inhibitory activity on the norepinephrine transporter (NET) of extremely weak (IC₅₀ > 1000 nM); it has low affinity for subtypes such as 5-HT₁B (Kᵢ = 490 nM) and 5-HT₁D (Kᵢ = 81 nM), showing high selectivity. LY 367265 concentration-dependently enhances of [³H]5-HT efflux (EC₅₀ = 250 nM). LY 367265 antagonizes the contraction response of Sumatriptan (HY-B0121B), indicating its functional antagonistic activity on 5-HT₁D-like receptors. LY 367265 can be used for the study of diseases such as anxiety disorders and post-traumatic stress disorder .
Cat. No.: HY-P3100
CAS No.: 939960-34-6
Cat. No.: HY-A0019AS
CAS No.: 1794685-21-4
Synonyms: 9-Hydroxyrisperidone palmitate-d4
Cat. No.: HY-W740297
CAS No.: 1189992-73-1
Cat. No.: HY-125357
CAS No.: 148619-41-4
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
