17 Results for "

6-phosphogluconate dehydrogenase

" in MedChemExpress (MCE) Product Catalog:
Products (17)

17 Results for "6-phosphogluconate dehydrogenase" in MCE Product Catalog:

10
10 Publications Verification
Cat. No.: HY-N0108
CAS No.: 521-61-9
Synonyms: Parietin; Rheochrysidin
Physcion (Parietin), an anthraquinone derivative derived from the traditional Chinese medicine rhubarb, is an effective oral active 6-phosphogluconate dehydrogenase inhibitor with blood-brain barrier permeability, with IC50 and Kd values of 38.5 μM and 26.0 μM, respectively. Additionally, Physcion is an inhibitor of the <>bTLR4/NF-κB signaling pathway, exhibiting anti-inflammatory, antibacterial, and anticancer effects, and can induce Apoptosis and Autophagy in cancer cells .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-B0157
CAS No.: 34580-13-7
Synonyms: HC 20-511
Ketotifen (HC 20-511) is an orally active second-generation noncompetitive histamine 1 (H1) receptor blocker and mast cell stabilizer. Ketotifen can block 6-phosphogluconate dehydrogenase (PGD) in vitro. Ketotifen also has antiviral activity against SARS-CoV-2 and Influenza virus. Ketotifen can be used to the research of autoimmune encephalomyelitis (EAE) and asthma attack prevention .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-B0157A
CAS No.: 34580-14-8
Synonyms: HC 20511 fumarate
Ketotifen (HC 20-511) fumarate is an orally active second-generation noncompetitive histamine 1 (H1) receptor blocker and mast cell stabilizer. Ketotifen fumarate can block 6-phosphogluconate dehydrogenase (PGD) in vitro. Ketotifen fumarate also has antiviral activity against SARS-CoV-2 and Influenza virus. Ketotifen fumarate can be used to the research of autoimmune encephalomyelitis (EAE) and asthma attack prevention .
loading...
    loading...
Cat. No.: HY-N7850
CAS No.: 5539-66-2
Synonyms: 1-Hydroxy-8-methoxyanthraquinone
Target:  

Endogenous Metabolite

Research Areas:  

Cancer

6PGD-IN-1 (compound S3) is an inhibitor of 6-phosphogluconate dehydrogenase (6PGD). IC50 and Kd the value of 17.8μM and 17.1 μM respectively. 6PGD-IN-1 has antitumor activity .
loading...
    loading...
Cat. No.: HY-P3175
CAS No.: 9073-95-4
Synonyms: 6-phosphogluconate dehydrogenase
Research Areas:  

Metabolic Disease

Phosphogluconate dehydrogenase (NADP, decarboxylating) (6-Phosphogluconate dehydrogenase) is an oxidative carboxylase that catalyses the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate in the context of the oxidative part of the pentose phosphate pathway .
loading...
    loading...
Cat. No.: HY-N0108R
CAS No.: 521-61-9
Synonyms: Parietin (Standard); Rheochrysidin (Standard)
Physcion (Standard) is the analytical standard of Physcion. This product is intended for research and analytical applications. Physcion (Parietin) is an anthraquinone isolated from traditional Chinese medicine Radix et Rhizoma Rhei, acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC50 and a Kd of 38.5 μM and 26.0 μM, respectively . Physcion (Parietin) exhibits laxative, hepatoprotective, anti-inflammatory, anti-microbial, anti-proliferative and anti-tumor effects .
loading...
    loading...
Cat. No.: HY-W726137
CAS No.: 5908-27-0
Target:  

Drug Intermediate

Research Areas:  

Infection

Potassium 1,2-naphthoquinone-4-sulphonate (Compound 16) is a 6-phosphogluconate dehydrogenase (6PGDH) inhibitor with an IC50 of 53 μM. Potassium 1,2-naphthoquinone-4-sulphonate can be used in the study of human African trypanosomiasis .
loading...
    loading...
Cat. No.: HY-B0157AR
CAS No.: 34580-14-8
Synonyms: HC 20511 fumarate (Standard)
Ketotifen (fumarate) (Standard) is the analytical standard of Ketotifen (fumarate). This product is intended for research and analytical applications. Ketotifen (HC 20-511) fumarate is an orally active second-generation noncompetitive histamine 1 (H1) receptor blocker and mast cell stabilizer. Ketotifen fumarate can block 6-phosphogluconate dehydrogenase (PGD) in vitro. Ketotifen fumarate also has antiviral activity against SARS-CoV-2 and Influenza virus. Ketotifen fumarate can be used to the research of autoimmune encephalomyelitis (EAE) and asthma attack prevention .
loading...
    loading...
Cat. No.: HY-N0108S
CAS No.: 1215751-27-1
Synonyms: Parietin-d3; Rheochrysidin-d3
Physcion-d3 (Parietin-d3) is the deuterium labeled Physcion (HY-N0108). Physcion acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC50 and a Kd of 38.5 μM and 26.0 μM, respectively. Physcion exhibits laxative, hepatoprotective, anti-inflammatory, anti-microbial, anti-proliferative and anti-tumor effects .
loading...
    loading...
Cat. No.: HY-P81982
Synonyms: 6-phosphogluconate dehydrogenase; decarboxylating

Host:  

Rabbit

Application:  

WB, ICC/IF, IP

Reactivity:  

Human, Mouse, Rat

loading...
    loading...
Cat. No.: HY-B0157R
CAS No.: 34580-13-7
Synonyms: HC 20-511 (Standard)
Ketotifen (Standard) is the analytical standard of Ketotifen. This product is intended for research and analytical applications. Ketotifen (HC 20-511) is an orally active second-generation noncompetitive histamine 1 (H1) receptor blocker and mast cell stabilizer. Ketotifen can block 6-phosphogluconate dehydrogenase (PGD) in vitro. Ketotifen also has antiviral activity against SARS-CoV-2 and Influenza virus. Ketotifen can be used to the research of autoimmune encephalomyelitis (EAE) and asthma attack prevention .
loading...
    loading...
Cat. No.: HY-175492
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

6PGD-IN-2 is an uncompetitive 6-phosphogluconate dehydrogenase (6PGD) inhibitor with an IC50 of 5.1 μM. 6PGD-IN-2 disrupts 6PGD oligomerization in a substrate-dependent manner. 6PGD-IN-2 results in a decrease of NADPH and Ru-5-P production as well as DNA synthesis in A549 cells. 6PGD-IN-2 can used for the studies of non-small cell carcinoma and liver cancer .
loading...
    loading...
Cat. No.: HY-B0157S1
CAS No.: 126939-17-1
Synonyms: HC 20-511-d3
Ketotifen-d3 (HC 20-511-d3) is deuterium labeled Ketotifen. Ketotifen (HC 20-511) is an orally active second-generation noncompetitive histamine 1 (H1) receptor blocker and mast cell stabilizer. Ketotifen can block 6-phosphogluconate dehydrogenase (PGD) in vitro. Ketotifen also has antiviral activity against SARS-CoV-2 and Influenza virus. Ketotifen can be used to the research of autoimmune encephalomyelitis (EAE) and asthma attack prevention .
loading...
    loading...
Cat. No.: HY-P81982A
Synonyms: 6-phosphogluconate dehydrogenase; decarboxylating

Host:  

Rabbit

Application:  

WB, ICC/IF, IP

Reactivity:  

Human, Mouse, Rat

loading...
    loading...
Cat. No.: HY-P73376
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: PGD; phosphogluconate dehydrogenase (NADP(+)-Dependent, Decarboxylating); phosphogluconate dehydrogenase; 6PGD; 6-phosphogluconate dehydrogenase, Decarboxylating; PGDH
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P7450
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PGD; phosphogluconate dehydrogenase (NADP(+)-Dependent, Decarboxylating); phosphogluconate dehydrogenase; 6PGD; 6-phosphogluconate dehydrogenase, Decarboxylating; PGDH
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-W611983
CAS No.: 13100-82-8
Research Areas:  

Others

DL-Cysteic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
loading...
    loading...
  • 1