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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
AG3
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "AG3" in MCE Product Catalog:
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Research Areas:
Icilin (AG-3-5) is a super-agonist of the transient receptor potential M8 (TRPM8) ion channel. Icilin activates TRPM8 in EGTA in a dose-dependent manner (EC50=1.4 μM). Icilin is a "super-cooling agent" . Icilin attenuates autoimmune neuroinflammation through modulation of the T-cell response [3].
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Cat. No.: HY-P11855
CAS No.: 557064-55-8
Cat. No.: HY-111297
CAS No.: 868843-84-9
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BMVC4 is a G-quadruplex (G4) stabilizer of the human telomeric sequence d[AG3(T2AG3)3]. Screening by circular dichroism (CD) spectroscopy revealed that BMVC4 is more suitable as the core molecule of G4 stabilizers than BMVC. The results showed that BMVC4-12C and BMVC4-8C3O are better candidates for G4 stabilizers and are worthy of further study. A simple and rapid screening method based on Cu2+-induced G4 unfolding can be used to find better G4 stabilizers for potential anticancer applications. CD results showed that the trivalent cations of 9-substituted BMVC derivatives are more suitable as G4 stabilizers than the divalent cations of BMVC. In addition, by monitoring the disappearance of the 291 nm CD band of human telomeres after Cu2+ addition, it was found that the core molecule of G4 stabilizer BMVC4 has better stability.
Cat. No.: HY-P76808
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Lymphocyte Function-Associated Antigen 3; Surface Glycoprotein LFA-3; LFA3; AG3; CD58 antigen
Species:
Source:
Cat. No.: HY-RS00463
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Research Areas:
AGR3 Human Pre-designed siRNA Set A contains three designed siRNAs for AGR3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS02256
Target:
Research Areas:
CD58 Human Pre-designed siRNA Set A contains three designed siRNAs for CD58 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS16435
Target:
Research Areas:
NBPF15 Human Pre-designed siRNA Set A contains three designed siRNAs for NBPF15 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
