16 Results for "

AMD1

" in MedChemExpress (MCE) Product Catalog:
Products (16)

16 Results for "AMD1" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P3252A
Target:  

Complement System

Research Areas:  

Inflammation/Immunology

Pegcetacoplan acetate is a pegylated complement C3/C3b inhibitor. Pegcetacoplan acetate acts by specifically binding to and inhibiting C3 and C3b, thereby suppressing the complement cascade at its proximal stage. Pegcetacoplan is not a known inhibitor or inducer of CYP450 isoenzymes. Pegcetacoplan acetate can be used for the research of complement-mediated diseases, including paroxysmal nocturnal hemoglobinuria (PNH) and age-related macular degeneration (AMD) .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-15492
CAS No.: 319460-94-1
Purity:  99.71%
Synonyms: AG-013958
Target:  

VEGFR

Research Areas:  

Cardiovascular Disease

AG-13958 (AG-013958), a potent VEGFR tyrosine kinase inhibitor, is used for treatment of choroidal neovascularization associated with age-related macular degeneration (AMD) .
loading...
    loading...
Cat. No.: HY-P99629
CAS No.: 2403683-24-7
Synonyms: FHTR 2163; RG 6147; RO 7171009

Target:  

Ser/Thr Protease

Research Areas:  

Neurological Disease

Galegenimab (FHTR 2163) is a humanized monoclonal antibody Fab fragment targeting the HtrA1 trimer. Galegenimab is used in research on age-related macular degeneration (AMD) .
loading...
    loading...
Cat. No.: HY-19720A
CAS No.: 1141934-97-5
Synonyms: ACU-4429 hydrochloride
Target:  

RPE65

Research Areas:  

Metabolic Disease

Emixustat (ACU-4429) hydrochloride is an orally active RPE65 inhibitor with an IC50 value of 4.4 nM. Emixustat hydrochloride is also a visual cycle modulator, capable of regulating visual cycle activity by inhibiting retinol isomerization, and holds potential for studying vision disorders such as age-related macular degeneration (AMD) .
loading...
    loading...
Cat. No.: HY-109561
CAS No.: 222716-86-1
Purity:  98.09%
Synonyms: EYE001; NX1838
Target:  

VEGFR

Pegaptanib sodium is an RNA aptamer with polyethylene glycol modifications, which is directed against vascular endothelial growth factor (VEGF)-165. Pegaptanib could be used for the study of neovascular age-related macular degeneration (AMD) .
loading...
    loading...
Cat. No.: HY-19720
CAS No.: 1141777-14-1
Synonyms: ACU-4429
Target:  

RPE65

Research Areas:  

Metabolic Disease

Emixustat is an orally active RPE65 inhibitor with an IC50 value of 4.4 nM. Emixustat is also a visual cycle modulator, capable of regulating visual cycle activity by inhibiting retinol isomerization, and holds potential for studying vision disorders such as age-related macular degeneration (AMD) .
loading...
    loading...
Cat. No.: HY-RS00644
Research Areas:  

Others

AMD1 Human Pre-designed siRNA Set A contains three designed siRNAs for AMD1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-N0679S
CAS No.: 118139-36-9
Synonyms: ALK-001; Retinol acetate-d3; Vitamin A acetate-d3
Retinyl acetate-d3 (ALK-001) is a deuterated Vitamin A. Retinyl acetate-d3 can be used for research of geographic atrophy (GA) secondary to age-related macular degeneration (AMD) .
loading...
    loading...
Cat. No.: HY-RS18124
Research Areas:  

Others

Amd1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Amd1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
loading...
    loading...
Cat. No.: HY-RS24598
Research Areas:  

Others

Amd1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Amd1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-132126
CAS No.: 848057-98-7
Purity:  99.87%
Target:  

SRPK

Research Areas:  

Others

SPHINX is a selective SRPK1 inhibitor with an IC50 value of 0.58 μM. SPHINX effectively reduces Choroidal Neovascularization (CNV) in vivo. SPHINX can be used for the research of (age-related macular degenaration) AMD .
loading...
    loading...
Cat. No.: HY-RS09498
Research Areas:  

Others

NPR2 Human Pre-designed siRNA Set A contains three designed siRNAs for NPR2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-P810846
Synonyms: AMD, AMD1, S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human, Mouse, Rat, Bovine

loading...
    loading...
Cat. No.: HY-W888515
Research Areas:  

Neurological Disease

mPEG-PCL is an amphiphilic biodegradable block copolymer composed of hydrophilic methoxy poly (ethylene glycol) (mPEG) and hydrophobic poly (ε-caprolactone) (PCL). mPEG-PCL possesses excellent biocompatibility and can form delivery carriers such as micelles and nanoparticles. Through its amphiphilic block structure, mPEG-PCL forms nanocarriers and encapsulates hydrophobic molecules, thereby enhancing the loading capacity of hydrophobic molecules, reducing burst release, and achieving sustained release. mPEG-PCL can be used in research on nanodelivery, tissue engineering, and ocular delivery systems related to age-related macular degeneration (AMD) .
loading...
    loading...
Cat. No.: HY-15492A
CAS No.: 319463-49-5
Synonyms: AG-013958 monohydrochloride
Target:  

VEGFR

Research Areas:  

Cardiovascular Disease

AG-13958 monohydrochloride, a potent VEGFR tyrosine kinase inhibitor, is used for treatment of choroidal neovascularization associated with age-related macular degeneration (AMD) .
loading...
    loading...
Cat. No.: HY-109561R
CAS No.: 222716-86-1
Synonyms: EYE001 (Standard); NX1838 (Standard)
Pegaptanib sodium (Standard) is the analytical standard of Pegaptanib (sodium) (HY-109561). This product is intended for research and analytical applications. Pegaptanib sodium is an RNA aptamer with polyethylene glycol modifications, which is directed against vascular endothelial growth factor (VEGF)-165. Pegaptanib could be used for the study of neovascular age-related macular degeneration (AMD) .
loading...
    loading...
  • 1