1. Others
  2. Others

Emixustat hydrochloride (Synonyms: ACU-4429 hydrochloride)

Cat. No.: HY-19720A Purity: 99.50%
Handling Instructions

Emixustat hydrochloride strongly inhibits 11-cis-retinol production with IC50 values of 232 ± 3 nM.

For research use only. We do not sell to patients.

Emixustat hydrochloride Chemical Structure

Emixustat hydrochloride Chemical Structure

CAS No. : 1141934-97-5

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 218 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
2 mg USD 132 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
5 mg USD 240 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
10 mg USD 384 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
50 mg USD 1320 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
100 mg USD 2100 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Other Forms of Emixustat hydrochloride:

  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

Emixustat hydrochloride strongly inhibits 11-cis-retinol production with IC50 values of 232 ± 3 nM. IC50 value: 232 nM [1] Target: 11-cis-retinol Emixustat hydrochloride is a novel visual cycle modulator, in healthy volunteers. Oral Emixustat was safe and well tolerated when administered once daily for 14 days with minimal systemic adverse events reported. Evaluation of emixustat in subjects with geographic atrophy associated with dry age-related macular degeneration.[2]

Clinical Trial
References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 3.3351 mL 16.6756 mL 33.3511 mL
5 mM 0.6670 mL 3.3351 mL 6.6702 mL
10 mM 0.3335 mL 1.6676 mL 3.3351 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

299.84

Formula

C₁₆H₂₆ClNO₂

CAS No.

1141934-97-5

SMILES

O[[email protected]](CCN)C1=CC(OCC2CCCCC2)=CC=C1.[H]Cl

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 44 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Emixustat hydrochloride
Cat. No.:
HY-19720A
Quantity: