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Emixustat hydrochloride (Synonyms: ACU-4429 hydrochloride)

Cat. No.: HY-19720A Purity: 99.50%
Data Sheet SDS Handling Instructions

Emixustat hydrochloride strongly inhibits 11-cis-retinol production with IC50 values of 232 ± 3 nM.

For research use only. We do not sell to patients.
Emixustat hydrochloride Chemical Structure

Emixustat hydrochloride Chemical Structure

CAS No. : 1141934-97-5

Size Price Stock Quantity
10 mM * 1 mL in DMSO $181 In-stock
2 mg $110 In-stock
5 mg $200 In-stock
10 mg $320 In-stock
50 mg $1100 In-stock
100 mg $1750 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Other Forms of Emixustat hydrochloride:

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Description

Emixustat hydrochloride strongly inhibits 11-cis-retinol production with IC50 values of 232 ± 3 nM. IC50 value: 232 nM [1] Target: 11-cis-retinol Emixustat hydrochloride is a novel visual cycle modulator, in healthy volunteers. Oral Emixustat was safe and well tolerated when administered once daily for 14 days with minimal systemic adverse events reported. Evaluation of emixustat in subjects with geographic atrophy associated with dry age-related macular degeneration.[2]

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References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 3.3351 mL 16.6756 mL 33.3511 mL
5 mM 0.6670 mL 3.3351 mL 6.6702 mL
10 mM 0.3335 mL 1.6676 mL 3.3351 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

299.84

Formula

C₁₆H₂₆ClNO₂

CAS No.

1141934-97-5

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 44 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
Emixustat hydrochloride
Cat. No.:
HY-19720A
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