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Emixustat hydrochloride  (Synonyms: ACU-4429 hydrochloride)

Cat. No.: HY-19720A Purity: 99.59%
COA Handling Instructions

Emixustat hydrochloride strongly inhibits 11-cis-retinol production with IC50 values of 232 ± 3 nM.

For research use only. We do not sell to patients.

Emixustat hydrochloride Chemical Structure

Emixustat hydrochloride Chemical Structure

CAS No. : 1141934-97-5

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 218 In-stock
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 218 In-stock
2 mg USD 132 In-stock
5 mg USD 240 In-stock
10 mg USD 384 In-stock
50 mg USD 1320 In-stock
100 mg USD 2100 In-stock
200 mg   Get quote  
500 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Emixustat hydrochloride:

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review


Emixustat hydrochloride strongly inhibits 11-cis-retinol production with IC50 values of 232 ± 3 nM. IC50 value: 232 nM [1] Target: 11-cis-retinol Emixustat hydrochloride is a novel visual cycle modulator, in healthy volunteers. Oral Emixustat was safe and well tolerated when administered once daily for 14 days with minimal systemic adverse events reported. Evaluation of emixustat in subjects with geographic atrophy associated with dry age-related macular degeneration.[2]

Clinical Trial
Molecular Weight









Room temperature in continental US; may vary elsewhere.


4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 44 mg/mL (146.74 mM)

*"≥" means soluble, but saturation unknown.

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3351 mL 16.6756 mL 33.3511 mL
5 mM 0.6670 mL 3.3351 mL 6.6702 mL
10 mM 0.3335 mL 1.6676 mL 3.3351 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
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Emixustat hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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