1. Protein Tyrosine Kinase/RTK
  2. VEGFR
  3. AG-13958

AG-13958 (Synonyms: AG-013958)

Cat. No.: HY-15492
Handling Instructions

AG-13958 (AG-013958), a potent VEGFR tyrosine kinase inhibitor, is used for treatment of choroidal neovascularization associated with age-related macular degeneration (AMD).

For research use only. We do not sell to patients.

AG-13958 Chemical Structure

AG-13958 Chemical Structure

CAS No. : 319460-94-1

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 468 In-stock
Estimated Time of Arrival: December 31
5 mg USD 425 In-stock
Estimated Time of Arrival: December 31
10 mg USD 720 In-stock
Estimated Time of Arrival: December 31
50 mg USD 2200 In-stock
Estimated Time of Arrival: December 31
100 mg USD 3700 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Description

AG-13958 (AG-013958), a potent VEGFR tyrosine kinase inhibitor, is used for treatment of choroidal neovascularization associated with age-related macular degeneration (AMD)[1].

IC50 & Target[1]

VEGFR

 

Molecular Weight

467.50

Formula

C₂₆H₂₂FN₇O

CAS No.

319460-94-1

SMILES

O=C(C1=CC(C)=NN1C)NC2=CC(NC3=CC4=C(C=C3)C(/C=C/C5=NC=CC=C5)=NN4)=CC=C2F

Shipping

Room temperature in continental US; may vary elsewhere

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 5 mg/mL (10.70 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1390 mL 10.6952 mL 21.3904 mL
5 mM 0.4278 mL 2.1390 mL 4.2781 mL
10 mM 0.2139 mL 1.0695 mL 2.1390 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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AG-13958
Cat. No.:
HY-15492
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