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Antimalarial agent1

" in MedChemExpress (MCE) Product Catalog:

17

Inhibitors & Agonists

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Biochemical Assay Reagents

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-111529
    Tafenoquine
    4 Publications Verification

    WR 238605

    Parasite Infection
    Tafenoquine (WR 238605) is an 8-aminoquinoline. Tafenoquine is an anti-malarial prophylactic agent .
    Tafenoquine
  • HY-106005
    MMV390048
    3 Publications Verification

    Parasite PI4K Infection
    MMV390048 is a representative of a new chemical class of Plasmodium PI4K inhibitor (Kd app=0.3 µM). MMV390048 binds to the ATP binding site of Plasmodium PI4K and does not bind to other P. falciparum and human kinases apart from human PIP4K2C, thus alleviating potential kinase-mediated safety concerns. MMV390048 is an antimalarial agent .
    MMV390048
  • HY-111529A
    Tafenoquine Succinate
    4 Publications Verification

    WR 238605 Succinate

    Parasite Infection
    Tafenoquine Succinate (WR 238605 Succinate) is an 8-aminoquinoline. Tafenoquine is an anti-malarial prophylactic agent .
    Tafenoquine Succinate
  • HY-W009109

    Parasite Infection
    Antimalarial agent 1 is a potent antimalarial agent .
    Antimalarial agent 1
  • HY-108640A

    MDM-2/p53 Parasite Apoptosis Infection Cancer
    HLI373 dihydrochloride is an efficacious Hdm2 inhibitor. HLI373 dihydrochloride inhibits the ubiquitin ligase activity of Hdm2. HLI373 dihydrochloride is effective in inducing apoptosis of several tumor cells that are sensitive to DNA-damaging agents . Antimalarial activity .
    HLI373 dihydrochloride
  • HY-108640

    MDM-2/p53 Parasite Apoptosis Infection Cancer
    HLI373 is an efficacious Hdm2 inhibitor. HLI373 inhibits the ubiquitin ligase activity of Hdm2. HLI373 is effective in inducing apoptosis of several tumor cells that are sensitive to DNA-damaging agents . Antimalarial activity .
    HLI373
  • HY-114197

    Mitochondrial Metabolism Parasite Infection
    Antimalarial agent 14 (Compound N3) is a potent inhibitor of mitochondrial electron transport. Antimalarial agent 14 can serve as an anti-malarial agent .
    Antimalarial agent 14
  • HY-N15562

    Parasite Infection
    Batzelladine L is a potent Plasmodium falciparum inhibitor (IC50= 0.4 μM). Batzelladine L shows moderate cytotoxicity to HepG2 cells (CC50= 14 μM) with antimalarial properties. Batzelladine L is promising for research of antimalarial agents .
    Batzelladine L
  • HY-111529AR

    WR 238605 Succinate (Standard)

    Parasite Reference Standards Infection
    Tafenoquine (Succinate) (Standard) is the analytical standard of Tafenoquine (Succinate). This product is intended for research and analytical applications. Tafenoquine Succinate (WR 238605 Succinate) is an 8-aminoquinoline. Tafenoquine is an anti-malarial prophylactic agent .
    Tafenoquine Succinate (Standard)
  • HY-147850

    Parasite Infection
    JMI-346 is a potent PfFP-2 (Plasmodium falciparum falcipain-2 protease) inhibitor. JMI-346 inhibits the growth of CQ S (3D7; IC50=13 µM) and CQ R (RKL-9; IC50=33 µM) strains of P. falciparum. JMI-346 has the potential to be used as an anti-malarial agent .
    JMI-346
  • HY-147849

    Parasite Infection
    JMI-105 is a potent PfFP-2 (Plasmodium falciparum falcipain-2 protease) inhibitor. JMI-105 inhibits the growth of CQ S (3D7; IC50=8.8 µM) and CQ R (RKL-9; IC50=14.3 µM) strains of P. falciparum. JMI-105 significantly decreases parasitemia and prolonged host survival in a murine model with P. berghei ANKA infection. JMI-105 has the potential to be used as an anti-malarial agent .
    JMI-105
  • HY-W131282

    Parasite Infection
    Antimalarial agent 39 (compound 1) is an intermediate in the synthesis of antimalarial agents .
    Antimalarial agent 39
  • HY-W072459

    Drug Metabolite Infection
    6'-Hydroxydihydrocinchonidine is a metabolite of Quinine (HY-D0143) (antimalarial agent) .
    6'-Hydroxydihydrocinchonidine
  • HY-W072459A

    Drug Metabolite Infection
    6'-Hydroxydihydrocinchonidine acetate is a metabolite of Quinine (HY-D0143) (antimalarial agent) .
    6'-Hydroxydihydrocinchonidine acetate
  • HY-113760

    (+)-Xestoquinone

    Parasite Infection
    Xestoquinone ((+)-Xestoquinone) is a Plasmodium falciparum protein kinase Pfnek-1 inhibitor (IC50=1.1 μM). Xestoquinone is promising for research of antimalarial agents .
    Xestoquinone
  • HY-W665882

    TNF Receptor Parasite Drug Metabolite Infection Inflammation/Immunology
    Norketotifen is the active metabolite of Ketotifen (HY-B0157). Norketotifen exhibits skin anti-inflammatory activity, anti-malarial activity, and antipruritic activity against non-histamine-mediated dog itching in mice. Norketotifen effectively inhibits TNF-α release without causing any sedative side effects. Norketotifen can be used for research on non-sedating anti-inflammatory agents .
    Norketotifen
  • HY-106005R

    Reference Standards Parasite PI4K Infection
    MMV390048 (Standard) is the analytical standard of MMV390048 (HY-106005). This product is intended for research and analytical applications. MMV390048 is a representative of a new chemical class of Plasmodium PI4K inhibitor (Kdapp=0.3 μM). MMV390048 binds to the ATP binding site of Plasmodium PI4K and does not bind to other P. falciparum and human kinases apart from human PIP4K2C, thus alleviating potential kinase-mediated safety concerns. MMV390048 is an antimalarial agent .
    MMV390048 (Standard)

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