34580-20-6
Chemical Structure
Norketotifen
- CAS No.: 34580-20-6
- Formula:C18H17NOS
- Molecular Weight:295.40
IUPAC Name: 4-(piperidin-4-ylidene)-4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one
InChIKey: IYSYPCSSDZBWHN-UHFFFAOYSA-N
SMILES: O=C1C2=C(/C(C3=C(C1)C=CC=C3)=C4CCNCC\4)C=CS2
Biological Activity: Norketotifen is the active metabolite of Ketotifen (HY-B0157). Norketotifen exhibits skin anti-inflammatory activity, anti-malarial activity, and antipruritic activity against non-histamine-mediated dog itching in mice. Norketotifen effectively inhibits TNF-α release without causing any sedative side effects. Norketotifen can be used for research on non-sedating anti-inflammatory agents[1].
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Norketotifen | Norketotifen is the active metabolite of Ketotifen (HY-B0157). Norketotifen exhibits skin anti-inflammatory activity, anti-malarial activity, and antipruritic activity against non-histamine-mediated dog itching in mice. Norketotifen effectively inhibits TNF-α release without causing any sedative side effects. Norketotifen can be used for research on non-sedating anti-inflammatory agents. | |||||||||||||||||||||
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Ketotifen impurity 3-d4 | Ketotifen impurity 3-d4 is the deuterium labeled Ketotifen impurity 3. | |||||||||||||||||||||
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