Antimalarial agent 39
Based on 1 Customer Validation
Antimalarial agent 39 (compound 1) is an intermediate in the synthesis of antimalarial agents.
For research use only. We do not sell to patients.
- Purity: 97.26%
- CAS No.: 5407-57-8
- Formula: C11H12ClN3
- Molecular Weight:221.69
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Parasite Isoforms
More
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
63.44 μM
Compound: 16, n = 2
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Cytotoxicity against human HeLa cells by MTT assay
Cytotoxicity against human HeLa cells by MTT assay
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[PMID: 22858300] |
| HeLa | IC50 |
7.22 μM
Compound: 2a
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Cytotoxicity against human HeLa cells after 7 days by MTT assay
Cytotoxicity against human HeLa cells after 7 days by MTT assay
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[PMID: 21489789] |
| L6 | IC50 |
21.22 μM
Compound: 17a
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Cytotoxicity against rat L6 cells after 72 hrs by fluorometric analysis
Cytotoxicity against rat L6 cells after 72 hrs by fluorometric analysis
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[PMID: 24900574] |
| L929 | CC50 |
<194 μM
Compound: 5g
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Cytotoxicity against mouse L929 cells after 96 hrs by alamar blue assay
Cytotoxicity against mouse L929 cells after 96 hrs by alamar blue assay
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[PMID: 28215783] |
Chemical Information
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CAS No. 5407-57-8
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Appearance Solid
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Molecular Weight 221.69
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Formula C11H12ClN3
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Color White to off-white
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SMILES
C1=C(C=C2C(=C1)C(=CC=N2)NCCN)Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 12.5 mg/mL (56.39 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.5108 mL | 22.5540 mL | 45.1080 mL | 112.7701 mL |
| 5 mM | 0.9022 mL | 4.5108 mL | 9.0216 mL | 22.5540 mL | |
| 10 mM | 0.4511 mL | 2.2554 mL | 4.5108 mL | 11.2770 mL | |
| 15 mM | 0.3007 mL | 1.5036 mL | 3.0072 mL | 7.5180 mL | |
| 20 mM | 0.2255 mL | 1.1277 mL | 2.2554 mL | 5.6385 mL | |
| 25 mM | 0.1804 mL | 0.9022 mL | 1.8043 mL | 4.5108 mL | |
| 30 mM | 0.1504 mL | 0.7518 mL | 1.5036 mL | 3.7590 mL | |
| 40 mM | 0.1128 mL | 0.5639 mL | 1.1277 mL | 2.8193 mL | |
| 50 mM | 0.0902 mL | 0.4511 mL | 0.9022 mL | 2.2554 mL |
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