52 Results for "

BIG

" in MedChemExpress (MCE) Product Catalog:
Products (52)

52 Results for "BIG" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-13103
CAS No.: 956014-19-0
Purity:  99.51%
Target:  

Potassium Channel

Research Areas:  

Others

NS 11021 is a potent and specific Ca 2+-activated big-conductance K + Channels (KCa1.1 channels) activator. NS 11021 at concentrations above 0.3 μM activates KCa1.1 in a concentration-dependent manner by parallelshifting the channel activation curves to more negative potentials .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P4159
CAS No.: 133972-52-8
Target:  

ERK

Research Areas:  

Cardiovascular Disease

Endothelin-1 (1-31) (Human) is a potent vasoconstrictor and hypertensive agent. Endothelin-1 (1-31) (Human) is derived from the selective hydrolysis of big ET-1 by chymase .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P4159A
Target:  

ERK

Research Areas:  

Cardiovascular Disease

Endothelin-1 (1-31) (Human) TFA is a potent vasoconstrictor and hypertensive agent. Endothelin-1 (1-31) (Human) TFA is derived from the selective hydrolysis of big ET-1 by chymase .
loading...
    loading...
Cat. No.: HY-P3513
CAS No.: 77739-21-0
Target:  

ERK MMP

Research Areas:  

Neurological Disease

β-Neo-Endorphin is an endogenous opioid peptide. β-Neo-Endorphin is a hypothalamic “big” Leu-enkephalin of porcine origin. β-Neo-Endorphin shows activation of the Erk1/2, MMP-2 and MMP-9 .
loading...
    loading...
Cat. No.: HY-P2538
CAS No.: 120796-97-6
Target:  

Vasopressin Receptor

Research Areas:  

Cardiovascular Disease

Big Endothelin-1 (1-38), human is the precursor of endothelin-1. Endothelin-1 (ET-1) is a potent vasopressor peptide .
loading...
    loading...
Cat. No.: HY-P3733
CAS No.: 124932-61-2
Target:  

Endothelin Receptor

Research Areas:  

Cardiovascular Disease

Big Endothelin-1 (22-38), human is derived from human, is the 22-38 fragment of Big Endothelin-1 (ET-1) (1-38). Big ET-1 (1-38) is a propeptide of ET-1, which has potent and long-lasting vasoconstrictor effects, equips a specific enzymatic cleavage of the 38 amino acid chain to form ET-1 (1-21) and the C-terminal fragment Big ET-1 (22-38) .
loading...
    loading...
Cat. No.: HY-164652
CAS No.: 181147-28-4
Research Areas:  

Others

m-BBIG dihydrochloride is a member of Bis-iminoguanidine (BIG) family and can be utilized in synthetic chemistry .
loading...
    loading...
Cat. No.: HY-P4912
CAS No.: 2243219-82-9
Target:  

Peptides

Research Areas:  

Others

Big Endothelin-1 (rat) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
loading...
    loading...
Cat. No.: HY-P3569
CAS No.: 1206769-73-4
Target:  

Peptides

Research Areas:  

Others

[D-Val22, Phe33] Big Endothelin-1 (16-38), human is a polypeptide.
loading...
    loading...
Cat. No.: HY-P4915
CAS No.: 174283-52-4
Target:  

Peptides

Research Areas:  

Others

Big Endothelin-3 (22-41) amide (human) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
loading...
    loading...
Cat. No.: HY-15402
CAS No.: 210891-04-6
Synonyms: BMS 207940
Target:  

Endothelin Receptor

Research Areas:  

Cardiovascular Disease

Edonentan (BMS 207940) is an orally active, highly selective endothelin A receptor (ETA receptor) antagonist with a Ki value of 0.01 nM against human targets. Edonentan blocks the pressor response induced by Big Endothelin-1 in conscious normotensive rats and the pressor response induced by ET-1 in conscious normotensive cynomolgus monkeys. Edonentan can be used in research related to cardiovascular diseases .
loading...
    loading...
Cat. No.: HY-P3446A
Big Gastrin I, human (TFA) is a gastrointestinal hormone consisting of 34 amino acids. Big Gastrin I, human (TFA) can be used as a potential substance for the study of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurological diseases or cardiovascular diseases .
loading...
    loading...
Cat. No.: HY-P4159B
Target:  

ERK

Research Areas:  

Cardiovascular Disease

Endothelin-1 (1-31) (Human) acetate is a potent vasoconstrictor and hypertensive agent. Endothelin-1 (1-31) (Human) acetate is derived from the selective hydrolysis of big ET-1 by chymase .
loading...
    loading...
Cat. No.: HY-124234
CAS No.: 169679-53-2
Target:  

Endothelin Receptor

Research Areas:  

Cardiovascular Disease

TA-0201 is a novel orally active, competitive, non-peptide endothelin receptor antagonist. TA-0201 antagonizes the specific binding of [ 125I]ET-1 to cloned human receptors of ETA and ETB with Ki values of 15 pM and 41 nM, respectively. TA-0201 inhibits the pressor response to the exogenous big ET-1 .
loading...
    loading...
Cat. No.: HY-P5130
Target:  

Endothelin Receptor

Research Areas:  

Cardiovascular Disease

Big endothelin-1 (rat 1-39) is a 39-residues peptide. Big endothelin-1 (rat 1-39) induces diuretic and natriuretic response in conscious Sprague-Dawley rats. Big endothelin-1 (rat 1-39) raises blood pressure in mice .
loading...
    loading...
Cat. No.: HY-P3734
CAS No.: 142191-53-5
Target:  

Peptides

Research Areas:  

Others

Big Endothelin-2 (1-38), human is a polypeptide.
loading...
    loading...
Cat. No.: HY-P2539
CAS No.: 120796-99-8
Target:  

Vasopressin Receptor

Research Areas:  

Cardiovascular Disease

Big Endothelin-1 (1-39), porcine is the precursor of endothelin-1. Endothelin-1 (ET-1) is a potent vasopressor peptide. Big Endothelin-1 (1-39), porcine has similar pressor effects in vivo .
loading...
    loading...
Cat. No.: HY-W155121
CAS No.: 86303-22-2
Synonyms: N,N-Bis(3-D-gluconamidopropyl)cholamide
Big CHAP are aqueous micelles of anionic cholate analogues .
loading...
    loading...
Cat. No.: HY-P5080
CAS No.: 151853-67-7
Target:  

Peptides

Research Areas:  

Others

Big Endothelin-2 (human) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
loading...
    loading...
Cat. No.: HY-RS16601
Research Areas:  

Others

Wdr5 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Wdr5 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...