956014-19-0
956014-19-0
Chemical Structure
NS 11021
- CAS. Nr.: 956014-19-0
- Formula:C16H9BrF6N6S
- Molecular Weight:511.24
IUPAC Name: 1-(3,5-bis(trifluoromethyl)phenyl)-3-(4-bromo-2-(1H-tetrazol-5-yl)phenyl)thiourea
InChIKey: MDKAFDIKYQMOMF-UHFFFAOYSA-N
SMILES: S=C(NC1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)NC2=CC=C(Br)C=C2C3=NN=NN3
Biological Activity: NS 11021 is a potent and specific Ca2+-activated big-conductance K+ Channels (KCa1.1 channels) activator. NS 11021 at concentrations above 0.3 μM activates KCa1.1 in a concentration-dependent manner by parallelshifting the channel activation curves to more negative potentials[1].
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NS 11021 | 99.51% | NS 11021 is a potent and specific Ca2+-activated big-conductance K+ Channels (KCa1.1 channels) activator. NS 11021 at concentrations above 0.3 μM activates KCa1.1 in a concentration-dependent manner by parallelshifting the channel activation curves to more negative potentials. | ||||||||||||||||||||
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