1,3-Bis[3,5-bis(trifluoromethyl)phenyl]urea
Based on 1 Customer Validation
1,3-Bis[3,5-bis(trifluoromethyl)phenyl]urea is a potent activator of eIF2α kinase heme regulated inhibitor. 1,3-Bis[3,5-bis(trifluoromethyl)phenyl]urea reduces the abundance of eIF2·GTP·tRNAiMet ternary complex. 1,3-Bis[3,5-bis(trifluoromethyl)phenyl]urea inhibits cancer cell proliferation.
For research use only. We do not sell to patients.
- CAS No.: 3824-74-6
- Formula: C17H8F12N2O
- Molecular Weight:484.24
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Storage:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Biological Activity
Description
Cellular Effect
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | Inhibition |
5 %
Compound: TCMDC-123956
|
GSK_TCMDC: Percent inhibition of human HepG2 cell line. Test compounds present at 10uM.
GSK_TCMDC: Percent inhibition of human HepG2 cell line. Test compounds present at 10uM.
|
[PMID: 20485427] |
Chemical Information
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CAS No. 3824-74-6
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Appearance Solid
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Molecular Weight 484.24
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Formula C17H8F12N2O
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SMILES
O=C(NC=1C=C(C=C(C1)C(F)(F)F)C(F)(F)F)NC=2C=C(C=C(C2)C(F)(F)F)C(F)(F)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)