14 Results for "

Bcl-x

" in MedChemExpress (MCE) Product Catalog:
Products (14)

14 Results for "Bcl-x" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P80030
Synonyms: Bcl2L, BclX, Bcl2L1, Bcl-2-like protein 1, Bcl2-L-1, Apoptosis regulator Bcl-X

Host:  

Rabbit

Application:  

WB, ICC/IF, IHC-P, FC, IP

Reactivity:  

Human

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Cat. No.: HY-170935
Research Areas:  

Cancer

SRSF1-IN-1 is a SRSF1 inhibitor. SRSF1-IN-1 inhibits SRSF1 expression, thereby modulating the splicing of Bcl-x pre-mRNA. SRSF1-IN-1 inhibits the proliferation of various cancer cells. SRSF1-IN-1 induces apoptosis in gastric cancer cells, reduces Bcl-xl expression, and upregulates cleaved PARP and caspase 3. SRSF1-IN-1 induces autophagy and promotes cell death. SRSF1-IN-1 exhibits anti-tumor activity in a mouse gastric cancer xenograft model. SRSF1-IN-1 can be used for the research of various cancers including liver cancer, gastric cancer, breast cancer, colon cancer, glioma, and melanoma .
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Cat. No.: HY-P2040
CAS No.: 118399-22-7
Nodularin is a hepatotoxin, tumor promoter, and protein phosphatase inhibitor. Nodularin induces apoptosis (apoptosis) in normal cells (including caspase activation, upregulation of Bcl-XS, and upregulation of BAX/P53), triggers hyperphosphorylation of the MAPK/ERK, mTOR/S6K and p38 MAPK signaling pathways, and induces oxidative stress, endoplasmic reticulum membrane instability, peroxisome proliferation and increased lysosomal enzyme activity. Nodularin promotes DEN (HY-N7434)-initiated hepatocyte proliferation and adenoma formation, and inhibits proliferation, phagocytosis and chemotaxis of normal lymphocytes, oocyte maturation and vitellogenesis, as well as angiogenesis. Nodularin exhibits hepatotoxicity, reproductive and endocrine toxicity, and embryonic developmental toxicity in various animal models. Nodularin can be used in studies related to liver cancer, hepatotoxicity and reproductive endocrine toxicity .
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Cat. No.: HY-P72846A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Bcl2L1; Bcl-X; Bcl2 Like 1; Protein Phosphatase 1, Regulatory Subunit 52; Bcl2L; Bcl-XL; BclX; Bcl-XS; Apoptosis Regulator Bcl-X; Bcl-XL/S; Bcl-2-Like Protein 1; Bcl2-L-1; PPP1R52
Species:  
Source:  
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Cat. No.: HY-RS01423
Research Areas:  

Others

Bcl2l1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Bcl2l1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS01421
Research Areas:  

Others

BCL2L1 Human Pre-designed siRNA Set A contains three designed siRNAs for BCL2L1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS01422
Research Areas:  

Others

Bcl2l1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Bcl2l1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P7650
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Bcl2L1; Bcl-X; Bcl2 Like 1; Protein Phosphatase 1, Regulatory Subunit 52; Bcl2L; Bcl-XL; BclX; Bcl-XS; Apoptosis Regulator Bcl-X; Bcl-XL/S; Bcl-2-Like Protein 1; Bcl2-L-1; PPP1R52
Species:  
Source:  
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Cat. No.: HY-P81614
Synonyms: Bcl2L1; Bcl2L; BclX; Bcl-2-like protein 1; Bcl2-L-1; Apoptosis regulator Bcl-X

Host:  

Rabbit

Application:  

FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P86554
Synonyms: Bcl2L1; Bcl2L; BclX; Bcl-2-like protein 1; Bcl2-L-1; Apoptosis regulator Bcl-X

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P80030A
Synonyms: Bcl2L, BclX, Bcl2L1, Bcl-2-like protein 1, Bcl2-L-1, Apoptosis regulator Bcl-X

Host:  

Rabbit

Application:  

WB, ICC/IF, IHC-P, FC, IP

Reactivity:  

Human

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Cat. No.: HY-P72846
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Bcl2L1; Bcl-X; Bcl2 Like 1; Protein Phosphatase 1, Regulatory Subunit 52; Bcl2L; Bcl-XL; BclX; Bcl-XS; Apoptosis Regulator Bcl-X; Bcl-XL/S; Bcl-2-Like Protein 1; Bcl2-L-1; PPP1R52
Species:  
Source:  
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Cat. No.: HY-15867
CAS No.: 1020210-12-1
Synonyms: (+)-Meayamycin B
Research Areas:  

Cancer

Meayamycin B ((+)-Meayamycin B) is a potent SF3B1 inhibitor. Meayamycin B upregulates the proapoptotic Mcl-1S and downregulates Mcl-1L at the pre-mRNA splicing level. Meayamycin B does not regulate the alternative splicing of Bcl-x. Meayamycin B and ABT-737 (HY-50907) synergistically causes Apoptosis. Meayamycin B exhibits anticancer activity against non-small cell lung cancer .
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Cat. No.: HY-P702954
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BAD; Bcl-2-Like Protein 8; Bcl2 Associated Agonist Of Cell Death; Bcl2-L-8; Bcl2L8; Bcl2-Antagonist Of Cell Death Protein; BBC2; Bcl-X/Bcl-2 Binding Protein; Bcl-XL/Bcl-2-Associated Death Promoter; Bcl2-Binding Component 6; Bcl2-Associated Agonist Of Cell
Species:  
Source:  
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