Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
35 Results for "
C. difficile
" in MedChemExpress (MCE) Product Catalog:
Products (35)
35 Results for "C. difficile" in MCE Product Catalog:
4
4 Cited Publications
Synonyms: ACX-362E; GLS-362E
Target:
Research Areas:
Ibezapolstat (ACX-362E) is a first-in-class, orally active DNA polymerase IIIC (pol IIIC) inhibitor, with a Ki of 0.325 μM for the DNA pol IIIC from C. difficile. Ibezapolstat is developed for the research of C. difficile infection(CDI) .
2
1
Ridinilazole is a novel antibacterial with MICs range of 0.06-0.25 µg/mL (MIC90=8 µg/mL) against C. difficile.
1
1 Cited Publications
Cat. No.: HY-P1137
CAS No.: 955091-53-9
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P9929
CAS No.: 1246264-45-8
Synonyms: BLA761046; MBL-CDB1; MDX-1388
1
1 Cited Publications
Cat. No.: HY-P1108
CAS No.: 681260-70-8
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P1108A
Target:
Research Areas:
1
Target:
Research Areas:
CRS3123 is a potent and orally active narrow-spectrum antibiotic. CRS3123 inhibits bacterial methionyl-tRNA synthetase. CRS3123 has potent activity against Clostridium difficile (C. difficile) and aerobic Gram-positive bacteria but little activity against Gram-negative bacteria, including anaerobes. CRS3123 has the potential for the research of C. difficile infections .
Category:
Infection Microorganisms Anti-inflammation/Immunoregulatory Antibiotics Disease Research Antibacterial Disease Research Fields Beta-lactam Antibiotics
Target:
Target:
Research Areas:
Penicillin V (Phenoxymethylpenicillin) is a potent and orally active antibiotic. Penicillin V shows antibacterial activity for Streptococci, Clostridium difficile and staphylococcus aureus. Penicillin V has the potential for the research of otitis, sinusitis, pharyngitis and tonsillitis .
Cat. No.: HY-P99277
CAS No.: 1245634-25-6
Synonyms: Anti-C. difficile Toxin A Recombinant Antibody
Target:
Research Areas:
Synonyms: KRM-1648; ABI-1648
Target:
Research Areas:
Rifalazil (KRM-1648; ABI-1648), a rifamycin derivative, inhibits the bacterial DNA-dependent RNA polymerase and kills bacterial cells by blocking off the β-subunit in RNA polymerase . Rifalazil (KRM-1648; ABI-1648) is an antibiotic, exhibits high potency against mycobacteria, gram-positive bacteria, Helicobacter pylori, C. pneumoniae and C. trachomatis with MIC values from 0.00025 to 0.0025 μg/ml . Rifalazil (KRM-1648; ABI-1648) has the potential for the treatment of Chlamydia infection, Clostridium difficile associated diarrhea (CDAD), and tuberculosis (TB) .
Cat. No.: HY-172670
Spore germination-IN-1 (Compound 110) is an orally active spore germination inhibitor (IC50: 14 μM). Spore germination-IN-1 specifically inhibits the enzymatic activities of mature SleC and CspB on spores (Kd: 12 and 8 μM). Spore germination-IN-1 can be used in studies against C. difficile .
Target:
Research Areas:
ATPase-IN-2 is an ATPase inhibitor with an IC50 value of 0.9 μM. ATPase-IN-2 inhibits C. difficile toxin B (TcdB) glycohydrolase activity with an AC50 value of 30.91 μM. ATPase-IN-2 can be used for the research of ATP-related .
Cholic acid anilide, a Narylcholan-24-amide, is a potent inhibitor of C. difficile spore germination with an IC50 value of 1.8 μM in the spore germination assay conducted in Sodium phosphate media containing 6 mM Taurocholate (HY-B1131) and 12 mM Glycine (HY-Y0966). Cholic acid anilide has the potential for C. difficile infections research .
Cat. No.: HY-B0975S1
CAS No.: 2699607-22-0
Synonyms: Phenoxymethylpenicillin-d5 potassium salt
Cat. No.: HY-B0975AR
CAS No.: 87-08-1
Synonyms: Phenoxymethylpenicillin (Standard)
Target:
Research Areas:
Penicillin V (Standard) is the analytical standard of Penicillin V. This product is intended for research and analytical applications. Penicillin V (Phenoxymethylpenicillin) is a potent and orally active antibiotic. Penicillin V shows antibacterial activity for Streptococci, Clostridium difficile and staphylococcus aureus. Penicillin V has the potential for the research of otitis, sinusitis, pharyngitis and tonsillitis [4].
Cat. No.: HY-156283
CAS No.: 2804044-53-7
Target:
Research Areas:
Antibacterial agent 159 (Compound 6d) is an antibiotic. Antibacterial agent 159 can effective against impetigo and C. difficile infection (CDI). Antibacterial agent 159 has no observed recurrence for C. difficile and exertes a minimal impact on the beneficial gut microbiome .
Category:
Microorganisms Anti-inflammation/Immunoregulatory Antibiotics Disease Research Antibacterial Beta-lactam Antibiotics
Target:
Cat. No.: HY-163142
CAS No.: 3023114-93-1
Antibacterial agent 172 (Compound 6a) is a <,i>Clostridioides difficile (Cd) SpoVD inhibitor (IC50=89 nM) that effectively inhibits sporulation of Clostridioides difficile. Antibacterial agent 172 can be used in the study of bacterial infections .
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
